Senior Clinical Trial Manager

ICON plc

. Serve as the primary point of communication for assigned trial sites and facilitate internal client teaming to drive issue resolution .

Posted 9/21/2026full-timeRemote • Pennsylvania • United StatesSeniorWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in trial management, including site feasibility, recruitment strategy, and compliance with ICH-GCP standards. Proficient in managing complex Early Phase trials and maintaining strong communication with stakeholders and site staff.

Highest-signal resume keywords

Trial ManagementICH-GCP KnowledgeHemOnc ExperienceBudget ManagementSite Recruitment Strategy

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Trial ManagementSite FeasibilityBudget ForecastingData Quality ManagementCAPA ImplementationInformed Consent PreparationVendor ManagementDatabase LockingRisk ManagementStudy Documentation

Soft Skills

Communication SkillsTeam CollaborationProblem SolvingStakeholder EngagementTraining Facilitation

Tools & Technologies

CTMSETMFTrial Management SystemsLocal Study Supplies ManagementMonitoring Training Tools

Industry Keywords

Clinical TrialsHealth SciencesRegulatory ComplianceAdverse Event ReportingInspection Readiness

About the role

Key responsibilities & impact

Serve as the primary point of communication for assigned trial sites and facilitate internal client teaming to drive issue resolution
Maintain relationships with critical site stakeholders and provide a voice for sites to client teams
Contribute to site feasibility, site qualification visits, follow-up, and final site selection
Coordinate local team activities, recruitment planning, contingency and risk management, budget forecasting, and study-level documentation
Engage investigators and site staff throughout the trial and communicate status information and issues to stakeholders
Maintain and update trial management systems and analyze trial progress
Initiate corrective and preventive actions when trials deviate from plans
Contribute to site-level recruitment strategy and contingency planning
Manage country-level vendors, invoices, local study supplies, and vendor selection requests
Conduct local trial team meetings and facilitate monitoring training
Prepare and manage country- and site-specific informed consent forms
Ensure adverse events, serious adverse events, and product quality complaints are reported within required timelines
Maintain inspection readiness, essential documents, CTMS and eTMF/IF data, and archive records
Ensure site data quality and timely query resolution
Support CAPA implementation for audits, inspections, and quality visits
Ensure accurate finance reporting and proactive country/local budget management
Organize IEC/HA approvals with the local Start Up team
Provide systems/process training and contribute to process initiatives
Complete timely and accurate time reporting
Manage complex Early Phase trials with internal matrix clinical teams and sites

Requirements

What you’ll need

BA/BS degree
Degree in a health or science related field
3 - 5+ years of trial end to end management experience
Start-up & Database Locks/Cleaning experience preferred
HemOnc experience required
Strong working knowledge of ICH-GCP, company standard operating procedures, local laws and regulations, assigned protocols and associated protocol specific procedures
Strong IT skills in appropriate software and company systems
Proficient in speaking and writing the country language and English
Good written and oral communication skills as appropriate
Legally authorized to work in the United States
Must not require, now or in the future, sponsorship for employment visa status

Benefits

Comp & perks

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways