Senior Director, Commercial Forecasting – Artificial Intelligence

Immatics

. Own demand, revenue and patient-flow forecasting across Immatics’ portfolio from early pipeline opportunity assessment through launch readiness and in-line performance .

Posted 9/30/2026full-timeRemote • United StatesSenior💰 $240,000 - $280,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in AI applications within the life sciences sector, particularly in forecasting and commercial analytics. Proficient in building patient-based forecast models and leveraging advanced analytics tools to drive strategic decision-making.

Highest-signal resume keywords

AI Application in Life SciencesForecasting and Commercial AnalyticsPatient-Based Forecast ModelsAdvanced Excel ModelingPython and SQL Proficiency

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Applicant Tracking System Keywords

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Hard Skills

ForecastingCommercial AnalyticsMarket InsightsPatient-Based Forecast ModelsAI and Large Language ModelsPrompt EngineeringData Quality ControlExcel ModelingPythonSQL

Soft Skills

Independent OperationStakeholder Communication

Tools & Technologies

Power BITableauIQVIASymphony HealthKomodoDefinitive HealthcareSEERClinical Registries

Industry Keywords

Life SciencesBiotechPharmaOncologyCell and Gene TherapyRare DiseaseSpecialty DistributionRegulated EnvironmentPHI/HIPAAGDPR

Tech Stack

Tools & technologies

PythonSQLTableau

About the role

Key responsibilities & impact

Own demand, revenue and patient-flow forecasting across Immatics’ portfolio from early pipeline opportunity assessment through launch readiness and in-line performance
Serve as the Commercial organization’s in-house AI expert
Develop the Commercial AI roadmap across Marketing, Market Access, Medical Affairs and Field Operations
Identify, prioritize and sequence AI and generative-AI use cases across analytics, forecasting, market research, competitive intelligence, field enablement, content development, promotional review preparation, account and KOL intelligence, payer and policy monitoring, and CRM data quality
Design, build and own AI-powered operating systems for day-to-day Commercial operations
Re-engineer analytics workflows, including automated data ingestion and quality control, reconciliation, exception flagging, forecast and dashboard refreshes, self-service analytics, recurring reporting and insight generation, and agentic workflows
Evaluate AI platforms and vendors and run structured pilots against defined success criteria
Make defensible build-versus-buy recommendations
Partner with cross-functional commercial teams and report to the VP Commercial Analytics & Operations
Travel approximately 10–15%

Requirements

What you’ll need

Bachelor’s degree or equivalent years of experience
15+ years in life sciences consultancy, biotech, pharma or related
7 years of forecasting, commercial analytics or market insights
Expertise building patient-based and epidemiology-driven forecast models for pre-launch and in-line assets
Working knowledge of pharma/biotech data sources including IQVIA, Symphony Health, Komodo, Definitive Healthcare, specialty distributor and 867/852 data, SEER, clinical registries and syndicated market research
Hands-on experience applying AI and large language models to commercial problems in a regulated life sciences environment
Practical fluency with LLM platforms, prompt engineering, retrieval-augmented generation and agentic workflows
Understanding of PHI/HIPAA, GDPR, promotional review, data licensing terms and emerging AI regulation
Advanced Excel modeling; working proficiency in Python, SQL and Power BI/Tableau
Experience across the launch lifecycle in oncology, cell and gene therapy, rare disease or specialty/limited-distribution settings
Ability to operate independently and translate quantitative and technical work into recommendations for senior stakeholders
Direct experience forecasting an autologous CAR-T, TCR-T or other engineered cell therapy asset, including site activation and manufacturing-constrained demand models
Track record of establishing forecasting or commercial AI capabilities at a pre-commercial or newly commercial company
Exposure to global forecasting and market access/pricing analytics in specialty oncology
Must be authorized to work in the United States without current or future sponsorship
Successful background check, reference checks and pre-employment drug screening; additional role-related screenings may apply

Benefits

Comp & perks

Competitive rates for Health, Dental, and Vision Insurance
4 weeks of vacation, granted up front each year and prorated for first and last year of employment
12 company paid holidays
7 days of sick time
100% employer-paid life insurance up to 1x annual salary, up to one hundred thousand dollars
100% employer-paid short- and long-term disability coverage
401(k) with immediate eligibility and company match
Partially paid parental leave for eligible employees
Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance
Remote U.S. work arrangement
Equal opportunity and reasonable accommodation support