Immatics

Artificial Intelligence

• Own demand, revenue and patient-flow forecasting across Immatics’ portfolio from early pipeline opportunity assessment through launch readiness and in-line performance
• Serve as the Commercial organization’s in-house AI expert
• Develop the Commercial AI roadmap across Marketing, Market Access, Medical Affairs and Field Operations
• Identify, prioritize and sequence AI and generative-AI use cases across analytics, forecasting, market research, competitive intelligence, field enablement, content development, promotional review preparation, account and KOL intelligence, payer and policy monitoring, and CRM data quality
• Design, build and own AI-powered operating systems for day-to-day Commercial operations
• Re-engineer analytics workflows, including automated data ingestion and quality control, reconciliation, exception flagging, forecast and dashboard refreshes, self-service analytics, recurring reporting and insight generation, and agentic workflows
• Evaluate AI platforms and vendors and run structured pilots against defined success criteria
• Make defensible build-versus-buy recommendations
• Partner with cross-functional commercial teams and report to the VP Commercial Analytics & Operations
• Travel approximately 10–15%

Senior Director, Commercial Forecasting – Artificial Intelligence

Medical Director

• Build and lead the Medical Information function for launch and future pipeline growth
• Establish Medical Information strategy, infrastructure, content, governance, workflows, intake and triage processes, response standards, escalation pathways, and content lifecycle management
• Develop and maintain Medical Information SOPs, work instructions, training standards, and quality processes
• Define the Medical Information technology roadmap, including inquiry management, content repositories, literature surveillance, analytics, and appropriate AI-enabled tools
• Lead onboarding, integration, training, and ongoing management of the Medical Information call center vendor
• Own call center launch readiness, including systems, content, workflows, escalation pathways, safety and product complaint reporting, service levels, and business continuity
• Establish vendor training and certification processes
• Oversee complex and escalated inquiries and connect the vendor with internal scientific experts
• Establish vendor KPIs, quality monitoring, governance, audit readiness, and corrective-action processes
• Lead Medical Information content strategy and development of Standard Response Letters, custom medical responses, FAQs, and other scientific response materials
• Lead literature review, data synthesis, and responses to complex or novel unsolicited inquiries
• Support scientific congresses with inquiry coverage, reference materials, escalation planning, and post-congress content updates
• Lead development and lifecycle management of AMCP dossiers and other payer evidence resources
• Lead development and submission of evidence packages to the NCCN Drugs & Biologics Compendium
• Support evidence submissions for other oncology guidelines and clinical pathways
• Serve as a scientific reviewer in PRC/MLR/MRC
• Support post-approval long-term follow-up requirements for cellular therapies, including potential CIBMTR registry participation and postmarketing evidence activities
• Partner across Medical Affairs, Clinical, Safety, Regulatory, Legal/Compliance, Market Access, HEOR/RWE, Quality, and Commercial
• Bring Medical Information expertise to launch planning, including labeling readiness, content priorities, inquiry forecasting, training, and day-one readiness
• Establish Medical Information metrics and reporting, monitor inquiry trends and service performance, and translate insights into Medical Affairs strategy
• Share insights and performance updates with Medical Affairs leadership and cross-functional partners
• Build and develop the Medical Information organization, including internal talent, contractors, vendor support, medical writing, and technology capabilities
• Develop annual and longer-range plans, priorities, resource needs, and budgets
• Foster a culture of scientific quality, accountability, collaboration, and practical problem-solving

Senior Director, Medical Information

Clinical Operations

• Serve as operational deputy and strategic partner to the VP, Clinical Operations
• Lead day-to-day operations of the global Clinical Operations organization and act as primary delegate and decision-maker within established authority matrices
• Align Trial/Asset Operations, Site Operations, Biosample Operations, and Clinical Systems into one unified ecosystem
• Align sub-functions with corporate development milestones and portfolio timelines
• Maintain holistic visibility across the clinical portfolio and manage dependencies, critical paths, and resource constraints
• Establish early-warning frameworks to identify, escalate, and mitigate execution issues, protocol deviations, and trial bottlenecks
• Mentor clinical operations leads and asset directors while ensuring accountability
• Lead and develop the senior clinical operations leadership team; design succession plans and career pathways
• Cultivate a unified culture across US and Germany organizational footprints
• Drive performance calibration, talent acquisition, workforce planning, and organizational capability mapping
• Own portfolio capacity planning, headcount forecasting, and strategic resource deployment
• Oversee budget planning, accrual tracking, and financial forecasting
• Manage CRO/vendor selection, performance metrics, and governance frameworks
• Analyze and recommend insourcing versus outsourcing strategies
• Champion continuous improvement, business process optimization, and scalable clinical workflows
• Ensure adherence to ICH-GCP, FDA/EMA regulations, and global SOPs
• Lead inspection readiness frameworks, internal quality audits, and harmonized global data standards
• Implement predictive operational metrics, KPIs, and executive dashboards
• Co-architect and execute the future-state operating model for late-stage development and commercialization
• Lead enterprise-wide change management, capability integration, and digital/systems evolution, including CTMS, eTMF, and decentralized trial technologies
• Design and deploy repeatable organizational systems to eliminate recurring operational friction points

Executive Director, Clinical Operations

Clinical Research

• Oversee site management, monitoring oversight, and clinical trial operations activities
• Ensure compliance with GCP, regulatory requirements, and company SOPs
• Partner with Clinical Operations leadership to support clinical trial execution and monitoring activities
• Lead site feasibility, selection, initiation, and greenlight activities
• Develop and maintain study-specific operational plans, training materials, and monitoring documentation
• Oversee site engagement, regulatory submissions, and monitoring activities
• Review trial progress, patient recruitment, and data quality metrics, and implement actions to support study objectives
• Provide guidance and oversight to CRAs, including trip report review and training support
• Manage protocol and GCP deviations
• Contribute to continuous improvement of clinical operations processes and procedures
• Collaborate with cross-functional teams and clinical sites
• Travel domestically and internationally, up to 50%

Clinical Trial Manager

Learning and Development

• Design, implement, and drive training and onboarding programs for Commercial teams, focusing on field-based teams
• Cover disease state education, product knowledge, and competitive landscape to enable field readiness
• Prepare field teams for external scientific exchange on product, disease state, and cell therapy education
• Create and drive training programs on Immatics’ pipeline and PRAME as a tumor antigen target to enable launch readiness
• Evolve ongoing training materials to reinforce knowledge and update teams on new data
• Ensure training and development programs adhere to regulatory, legal, and compliance standards
• Apply adult learning principles and innovative digital platforms to create engaging, effective training programs
• Review and report metrics and feedback systems to evaluate training effectiveness and adapt based on insights and field performance
• Maintain a central repository of training materials and scientific resources for version control, consistency, and global accessibility
• Identify training gaps and field needs through insight gathering and feedback loops; translate them into actionable solutions
• Partner with cross-functional partners to align training and tools with corporate strategy
• Manage vendor partnerships supporting training platforms, content development, and delivery systems

Senior Manager, Learning & Development

Operations

• Lead the design and stand-up of Immatics’ Authorized Treatment Center authorization program
• Define qualification standards, SOPs, training curriculum, chain-of-identity and chain-of-custody controls, monitoring and audit plans
• Lead execution across the US authorized treatment center network
• Design and build the program and lead a team to activate the first wave of ATCs by launch readiness
• Grow a team to sustain the ongoing authorization pipeline
• Report to the VP, Launch Excellence, Strategy, & Operations
• Design the anzu-cel ATC authorization program, including qualification criteria, risk-based assessment tooling, monitoring, requalification triggers, suspension/disqualification pathways, and monitoring plans
• Develop SOPs governing ATC authorization, authorized-user training and system access, product receipt and handling, and deviation escalation
• Partner with Regulatory Affairs and Quality on risk mitigation and health authority questions
• Benchmark and harmonize treatment-center requirements with ASTCT, FACT, accreditation standards, and manufacturer requirements
• Support site selection and prioritization, ATC target lists, activation sequencing, and readiness tracking
• Lead remote and on-site treatment-center qualification assessments across clinical care, leukapheresis, cell processing, pharmacy, cryostorage, and toxicity-management infrastructure
• Drive centers to activation by closing qualification gaps and confirming first-patient readiness
• Report ATC readiness into launch governance and own the authorization line on the integrated launch readiness plan
• Develop and deliver anzu-cel treatment-center training for physicians, nurses, cell therapy coordinators, apheresis teams, and quality personnel
• Maintain the authorized-user registry and oversee access to product ordering and chain-of-identity systems
• Establish retraining triggers for label/process changes, staff turnover, and post-deviation remediation
• Support manufacturer-side oversight of chain of identity and chain of custody at treatment centers
• Define and verify workflows for product receipt, cryogenic storage, thaw, administration, labeling, and identity verification
• Assess treatment-center impact of changes to collection, courier tracking, order intake, and order processing
• Partner with Quality Assurance on deviations, investigations, CAPAs, change controls, and quality records
• Ensure center-facing activity complies with Immatics policy and applicable healthcare law
• Serve as internal authority on treatment-center operational readiness across Patient Supply, Quality, Manufacturing, Regulatory, Medical Affairs, Commercial, and IT
• Feed center-level insight into launch planning, including capacity constraints, referral dynamics, and operational barriers
• Represent Immatics with accreditation bodies and cell therapy center consortia
• Convene advisory boards of treatment-center practitioners
• Define the field ATC operations model, including territory design, headcount, span ratios, and hiring sequence
• Build and lead a regional ATC Operations field team and establish performance metrics

Senior Director, ATC Operations

Director

• Establish and lead the IT Commercial & Patient Operations function
• Enable the US commercial launch strategy and drive IT launch milestones
• Own the end-to-end IT Commercial and Medical Affairs roadmap
• Translate functional needs into an executable, governed technology portfolio
• Create the strategy and continuous development of the commercial IT landscape
• Own, refine, and execute the IT Commercial & Patient Operations strategy and roadmap
• Align system rollouts with commercial milestones and manage dependencies across functions, vendors, and global IT
• Deliver the commercial systems portfolio, including ecosystem expansion, sales operations, marketing hub, omnichannel engagement, patient operations, commercial analytics, market access hub and medical affairs
• Deliver the patient operations technology stack, including ATC portal, hub and patient services integrations, CRM, allocation and slot management, call center/telephony, and end-to-end patient and product journey tracking
• Establish the commercial data foundation, including master data management, commercial data warehouse and data lake, reporting and analytics, and AI-enabled use cases
• Drive integrations with enterprise systems
• Ensure compliance of commercial and patient-facing systems with GxP/CSV requirements, 21 CFR Part 11, SOX, transparency reporting, HIPAA, GDPR, and applicable cybersecurity requirements
• Manage vendors, external partners, and implementation providers across the commercial portfolio, including contract, budget, and performance management

Executive Director, IT Commercial

Therapist

• Lead the day-to-day operations of Immatics’ patient-specific cell therapy product order management function supporting the TCR T-cell therapy portfolio
• Build and oversee the Patient Operations team
• Ensure efficient, accurate, and empathetic case and order coordination across authorized treatment centers
• Build the customer service model during launch readiness
• Develop SOPs, define patient and cell therapy product order management expectations, and establish scalable operational infrastructure
• Direct daily operations of the customer-facing Patient Operations Team, including assignments, coverage, workflow monitoring, call center coverage, escalation resolution, and service-level adherence
• Create and manage staffing and scheduling models to optimize patient throughput and authorized treatment center experience
• Make decisions and solve problems affecting operational cases, product order processing, treatment scheduling, and therapy progression
• Monitor case and order activity, resolve escalations, and provide real-time support to Patient Operations Managers/Sr. Managers and authorized treatment centers
• Foster a high-performance, service-oriented, supportive team culture
• Provide coverage outside regular working hours, including holidays and weekends, as necessary
• Provide subject matter expertise and commercial business stakeholder support for the Product Ordering & Management platform
• Define, draft, and refine SOPs, work instructions, and training materials
• Track and report KPIs related to Patient Operations performance, scheduling, product-order execution, and case progression
• Identify trends and opportunities to optimize the patient journey
• Partner with cross-functional stakeholders and leadership to resolve operational gaps and improve order-handling efficiency
• Partner with Patient Access & Support to establish clear handoffs and coordinated end-to-end patient support
• Serve as an escalation point for complex patient cases and product orders
• Support team management, cross-functional meetings, treatment center partnerships, and launch activities through approximately 10–20% travel