Senior Clinical Trial Manager

Jade Biosciences

. Support the Director, Clinical Operations, in planning and operational execution of assigned clinical trials .

Posted 10/5/2026full-timeRemote • United StatesSenior💰 $180,000 - $195,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive experience in managing complex clinical trial activities, including vendor management, budget oversight, and compliance with regulatory standards. Proficient in coordinating cross-functional teams and maintaining an inspection-ready Trial Master File throughout the drug development process.

Highest-signal resume keywords

Clinical Trial ManagementVendor ManagementBudget OversightFDA RegulationsGood Clinical Practice

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial ManagementBudget ManagementRisk ManagementProtocol ImplementationRegulatory SubmissionsTrial Master File MaintenancePhase 1-3 Clinical TrialsCRO ManagementClinical Technology ApplicationsMedical Terminology

Soft Skills

CommunicationOrganizationCollaborationProblem-SolvingAttention to Detail

Tools & Technologies

EDCRTSMClinical Trial Management SystemsData Management ToolsBiostatistics Software

Industry Keywords

BiopharmaceuticalGood Clinical PracticeICH GuidelinesClinical OperationsDrug Development Process

About the role

Key responsibilities & impact

Support the Director, Clinical Operations, in planning and operational execution of assigned clinical trials
Coordinate day-to-day study activities across cross-functional partners, clinical sites, CROs, and vendors
Maintain study plans, timelines, budgets, risks, and key documentation
Oversee vendor deliverables, performance metrics, issue resolution, meeting governance, invoices, and scope tracking
Maintain clinical trial budgets and forecasts; review invoices, track spend, identify variances, and escalate financial risks
Maintain risk, issue, decision, and action logs; drive mitigation and resolution activities
Coordinate operational input into protocols, monitoring plans, informed consent forms, investigator brochures, manuals, and clinical study reports
Oversee study start-up, site activation, enrollment, conduct, monitoring, closeout, and inspection-readiness activities
Support investigator meetings and monitoring oversight
Build relationships with clinical sites, investigators, CROs, vendors, and internal stakeholders
Review study performance metrics and implement corrective and preventive actions
Ensure trial activities and documentation comply with protocols, Good Clinical Practice, regulations, contracts, and company procedures
Coordinate operational requirements and timelines across clinical supply, laboratories, data management, safety, biostatistics, medical monitoring, and regulatory activities
Maintain an accurate, inspection-ready Trial Master File and support audits, inspections, and quality oversight
Mentor Clinical Trial Associates and Clinical Trial Managers, contribute to process improvements, and prepare study updates for governance and senior leadership

Requirements

What you’ll need

Bachelor’s degree and 10+ years of related experience for Senior Clinical Trial Manager, or 7+ years of related experience for Clinical Trial Manager
Trial management experience within a biopharmaceutical company
Ability to manage complex clinical trial activities, timelines, vendors, budgets, risks, and cross-functional deliverables with appropriate independence and escalation
Experience supporting Phase 1 through Phase 3 clinical trials
Experience managing CROs and clinical vendors, including laboratories, RTSM, EDC, and ancillary clinical technology or applications
Strong working knowledge of FDA regulations, ICH guidelines, Good Clinical Practice, medical terminology, and clinical trial conduct
Working knowledge of clinical protocol implementation, regulatory submissions, Trial Master File requirements, and the overall drug development process
Excellent communication, organization, collaboration, problem-solving, and attention-to-detail skills, with the ability to manage competing priorities
Authorization to work in the United States verified through Form I-9 and E-Verify

Benefits

Comp & perks

Remote work
Periodic travel to team and company events
Equal Opportunity employment