Jasper Therapeutics

Project Manager

• Support the planning, coordination, and execution of CMC activities across development programs
• Partner with CMC functional leads, cross-functional teams, and CDMOs to translate CMC strategy into integrated project plans
• Develop and maintain integrated CMC project plans, complex timelines, and Gantt charts
• Track CMC activities, milestones, deliverables, dependencies, commitments, risks, issues, and scope changes
• Identify schedule risks, resource constraints, dependencies, and potential delays; escalate issues to leadership
• Maintain project dashboards and provide status updates to management and project teams
• Plan, organize, and facilitate internal CMC/Technical Operations meetings
• Prepare meeting minutes and maintain action-item and decision logs
• Serve as the project-management interface between Technical Operations/CMC and Clinical, Regulatory, Quality, Finance, Legal, and Program Management
• Coordinate CMC timelines with clinical and regulatory development plans
• Support portfolio planning, management reporting, and executive-level reviews
• Develop and maintain CMC project budgets and forecasts
• Review and track vendor/CDMO invoices against contracts, statements of work, purchase orders, milestones, and payment schedules
• Maintain financial trackers and support budget planning, reforecasting, and long-range financial planning
• Establish and maintain organized CMC electronic filing and document-management structures
• Organize CMC SharePoint folders and maintain filing conventions for project, manufacturing, analytical, stability, regulatory, contract, meeting, budget, and vendor documentation

Senior Director, CMC Project Management

Operations

• Serve as CMC Program Leader for assigned clinical-stage development programs
• Translate Technical Operations and product-development strategy into integrated CMC development plans and execute them successfully
• Provide hands-on leadership for designated programs
• Support Analytical Development and Quality Control (AD/QC) across the Jasper product portfolio
• Lead technical activities conducted through CDMOs and CROs
• Partner with Supply Chain, Device/Combination Product, Quality, Regulatory Affairs, Clinical Operations, and Project Management to ensure CMC readiness for clinical development
• Serve as primary point of contact for all CMC activities supporting the ongoing Phase 2 clinical program in China
• Plan and execute local/regional clinical drug supply and device activities
• Coordinate with Clinical Operations, Supply Chain, and external partners to ensure timely clinical supply availability
• Support drug product manufacturing, release, packaging/labeling, shipment, inventory, and expiry management for local clinical trials
• Identify and resolve CMC and supply-related issues affecting clinical trial timelines
• Support device and combination-product activities for assigned clinical programs
• Serve as KP701 CMC Program Lead
• Translate clinical and regulatory objectives into executable CMC activities, milestones, timelines, budgets, and deliverables
• Oversee drug substance and drug product development and manufacturing

Executive Director, CMC Development – Technical Operations

Financial Planning and Analysis

• Report to the VP Finance
• Lead annual budgets, financial forecasts, and long-range planning aligned with company strategy
• Analyze current and past trends in key performance indicators
• Monitor performance indicators, analyze unexpected variances, and provide monthly and quarterly financial reviews
• Own the end-to-end CRO and CMO accrual process with Clinical Operations and CMC/Manufacturing
• Review CRO/CMO contracts, change orders, and purchase orders to validate expense recognition
• Flag budget-to-contract variances to Clinical Operations and Accounting leadership
• Serve as primary FP&A/accrual owner for quarterly reviews and year-end audit
• Prepare accrual support schedules and respond to external auditor requests
• Build and maintain trial-level and program-level R&D spend forecasts
• Support cash runway and burn-rate reporting to the Board and senior management
• Develop financial models and analyses for strategic initiatives and executive decision-making
• Prepare presentations for the Board of Directors and Senior Management Team
• Manage planning and review processes supporting financial reporting and controls compliance
• Improve budgeting, forecasting, operating plan, and modeling tools
• Enhance, implement, and enforce organizational policies and procedures through improved systems
• Collaborate with department leaders on overall goals and objectives
• Lead financial modeling and analysis for potential mergers, acquisitions, and investment opportunities

Senior Director, CMC Project Management

Executive Director, CMC Development – Technical Operations

Senior Manager, Financial Planning & Analysis