Director, Global Value and Health Economics

Jazz Pharmaceuticals

. Define and execute global and US payer evidence strategies in Oncology .

Posted 11/5/2026full-timeRemote • United States, United KingdomLead💰 $212,000 - $318,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Health Economics and Outcomes Research (HEOR) with a focus on developing and executing payer evidence strategies in Oncology. Proven ability to lead cross-functional teams and manage complex deliverables while ensuring compliance with regulatory standards.

Highest-signal resume keywords

Health Economics ModelingUS Payer Communication ComplianceOncology Evidence StrategiesAMCP Dossier DevelopmentCross-Functional Collaboration

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Health EconomicsOutcomes ResearchPharmacoeconomicsEconomic ModelingValue AssessmentClinical Trial Protocol OptimizationRare Disease Evidence GenerationPublication StrategyBudget ManagementStatistical Analysis

Soft Skills

LeadershipMentoringCollaborationCommunicationStrategic Thinking

Tools & Technologies

Economic ModelsInteractive ToolsDigital ToolsStatistical SoftwareData Visualization Tools

Certifications & Qualifications

Master’s Degree in Health EconomicsPhD in Health EconomicsMPH in Health Economics

Industry Keywords

OncologyManaged CareMedicareMedicaidHTAICERNCCNValue-Based ContractsBiopharmaceutical IndustryClinical Development

About the role

Key responsibilities & impact

Define and execute global and US payer evidence strategies in Oncology
Lead global HEOR activities and strategies in gastroesophageal adenocarcinoma and prepare assets for commercial and reimbursement milestones worldwide
Serve as lead HEOR partner for an Oncology asset’s expanding clinical pipeline and embed payer and HTA requirements into Phase 2 and Phase 3 programs
Serve as designated US HEOR lead, translating access and reimbursement priorities into evidence strategies supporting commercial, Medicare, and Medicaid access
Execute and author AMCP dossiers, US commercial/Medicare budget impact models, and state Medicaid submission packages
Partner with US Payer Field Teams to develop customer-facing economic models, slide decks, and digital tools
Monitor US health policy and prepare evidence roadmaps for value assessments such as ICER reviews and NCCN Evidence Blocks
Collaborate on innovative payment models and value-based contracts
Integrate payer, HTA, and reimbursement evidence requirements into clinical trial protocols
Optimize trial protocols, comparators, inclusion/exclusion criteria, lines of therapy, and payer-recognized endpoints
Integrate PROs, HRQoL, and HCRU measures into pivotal trials
Develop rare disease evidence strategies addressing small samples, heterogeneous presentations, single-arm studies, and surrogate endpoints
Formulate and execute health economic modeling strategies, including CEA, CUA, and BIM
Design and validate adaptable global core economic models for EU/INT HTA submissions and US payer use
Lead global payer evidence assets, including GVDs, SLRs, and global evidence libraries
Co-deliver HTA evidence packages, including ITCs, NMAs, and economic model adaptations, with the EU/INT HEOR team
Design and deliver RWE, natural history, burden-of-illness, treatment-pattern, and comparative-effectiveness studies
Lead HEOR launch readiness, lifecycle management, label expansion, and post-launch evidence programs
Govern IEGP HEOR commitments and align evidence plans with Market Access, Brand Teams, and Medical Affairs
Lead publication strategy, author peer-reviewed manuscripts, and present at scientific and health economic congresses
Mentor junior scientists, cross-functional colleagues, and HEOR fellows
Ensure evidence generation and communications comply with legal, regulatory, and corporate standards

Requirements

What you’ll need

Required Master’s degree (MSc, MS, MPH, PhD) in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field
Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm
Deep working knowledge of US managed care archetypes, including commercial health plans, PBMs, Medicare Part B/D, and Medicaid
Thorough familiarity with US payer communication compliance standards, including FDAMA Section 114 and the 21st Century Cures Act
Advanced expertise in health economic modeling, including Markov state-transition models, partitioned survival models, microsimulation, and discrete event simulation
Demonstrated track record partnering with US Payer Field Teams to develop interactive economic models and value presentation tools
Practical understanding of rare disease evidence generation challenges, including small patient samples, registry utilization, natural history studies, external control arms, and orphan drug HTA mechanisms
Proven track record leading HEOR workstreams for global and US launch preparation, lifecycle management, label expansions, and value defense
Demonstrated experience collaborating with Clinical Development and Biostatistics teams on Phase 2/3 study designs, comparator selection, and HEOR/PRO endpoints
Strong understanding of US health policy developments and experience preparing for or responding to value assessment bodies such as ICER
Proven ability to set global and US evidence strategies while directly executing complex deliverables such as AMCP dossiers, GVDs, NMAs, economic models, and RWE protocols
Ability to lead and collaborate cross-functionally across Clinical Development, Medical Affairs, Market Access, Regulatory, and Commercial without formal authority
Experience managing multi-million-dollar research budgets, vendor selection, and external CROs and academic partners
Experience with oncology assets preferred
Launch lead for at least 2 assets as US HEOR lead or country-level HTA lead
Strong peer-reviewed publication record in health economics and outcomes research

Benefits

Comp & perks

Discretionary annual cash bonus or incentive compensation
Discretionary equity grants
Medical insurance
Dental insurance
Vision insurance
401k retirement savings plan
Flexible paid vacation