Director, Global Value and Health Economics – Outcomes Research

Jazz Pharmaceuticals

. Lead global and US payer evidence strategy across marketed assets in Jazz’s neurology portfolio .

Posted 10/31/2026full-timeRemote • Pennsylvania • United StatesLead💰 $212,000 - $318,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Health Economics and Outcomes Research (HEOR) with a focus on post-marketing strategies, economic modeling, and evidence generation for biopharmaceutical products. Proven ability to collaborate across teams and manage complex deliverables while ensuring compliance with regulatory standards.

Highest-signal resume keywords

Health Economics ExpertisePost-Marketing HEOR StrategyEconomic Modeling ProficiencyUS Managed Care KnowledgeRegulatory Compliance Experience

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Comparative Effectiveness StudiesEconomic Models DevelopmentBudget Impact ModelingReal-World Evidence GenerationStatistical AnalysisSystematic Literature ReviewsMeta-AnalysesDossier PreparationEpidemiological MethodsPatient Registry Studies

Soft Skills

Exceptional Communication SkillsLeadership and MentoringCollaborationPresentation SkillsStrategic Thinking

Tools & Technologies

IQVIAOptumMarketScanMedicare SAFElectronic Health Records

Industry Keywords

Biopharmaceutical IndustryHealth Technology Assessment (HTA)Managed Care LandscapeRare DiseasesOncology Assets

About the role

Key responsibilities & impact

Lead global and US payer evidence strategy across marketed assets in Jazz’s neurology portfolio
Maximize brand potential, defend product value, secure expanded access, and drive post-launch evidence generation
Lead HEOR evidence strategies for supplemental regulatory filings, new indications, line extensions, expanded populations, and novel formulations/devices
Partner with Medical Affairs, Clinical Development, and Biostatistics on Phase 3b/4 trials, pragmatic studies, PROs, and HRQoL measures
Develop indication sequencing and access strategies with Market Access
Collaborate on rare disease registries, natural history extensions, and post-authorization safety/efficacy studies
Design comparative effectiveness, adherence, and burden-of-illness studies to defend product differentiation
Co-create HTA reassessment strategies and analytical packages with EU/INT HEOR teams
Direct updates to Global Value Dossiers, systematic literature reviews, and meta-analyses
Serve as designated US HEOR expert for assigned inline products
Lead AMCP dossiers, unbranded value summaries, and state Medicaid submission dossiers
Develop and train teams on interactive economic models and reactive scientific presentations
Ensure US HEOR materials comply with FDAMA Section 114, the 21st Century Cures Act, and FDA HCEI guidance
Evaluate outcomes-based risk-sharing agreements and establish real-world endpoint tracking frameworks
Monitor US health policy and prepare evidence plans for ICER and other value assessment bodies
Build and adapt cost-effectiveness, cost-utility, budget impact, cost-offset, Markov, partitioned survival, microsimulation, and dynamic budget impact models
Represent GVHEOR in IEGP governance and align post-marketing studies with brand objectives
Drive post-marketing HEOR publications and present findings at scientific congresses
Manage budgets, external HEOR consultancies, academic partners, and CROs
Mentor associate directors, managers, and fellows

Requirements

What you’ll need

Master’s degree (MSc, MS, MPH) or PhD in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field
Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm
Extensive experience designing and executing post-marketing HEOR strategies, real-world comparative effectiveness studies, and evidence roadmaps supporting label expansions, line extensions, and value defense
Comprehensive working knowledge of the US managed care landscape and global HTA environments
Proven technical expertise building, adapting, and validating economic models, including Markov, partitioned survival, microsimulation, and dynamic budget impact models
Proven track record collaborating with US Market Access, Pricing/Contracting, and Payer Field Teams to develop compliant customer-facing tools, interactive budget models, and AMCP dossiers
Demonstrated understanding of rare disease/orphan product post-launch evidence challenges
Working knowledge of major US and global healthcare databases, including IQVIA, Optum, MarketScan, Medicare SAF, disease-specific registries, and electronic health records
Advanced epidemiological methods for comparative research
Demonstrated ability to work with regional HEOR teams, especially EU/INT
Ability to execute complex technical deliverables including dossiers, models, observational research protocols, and publications
Exceptional verbal, written, and presentation skills
Required launch leadership for at least 2 assets as US HEOR lead or country-level HTA lead
Proven track record leading HEOR strategy and executing evidence deliverables for marketed pharmaceutical products
Experience conducting post-marketing RWE, patient registry studies, and economic evaluations in rare diseases, specialized medicine, or complex chronic conditions
Strong peer-reviewed publication record in health economics and outcomes research
Experience with oncology assets preferred

Benefits

Comp & perks

Discretionary annual cash bonus or incentive compensation
Discretionary equity grants through the Long Term Equity Incentive Plan
Medical insurance
Dental insurance
Vision insurance
401k retirement savings plan
Flexible paid vacation