Director, Global Value and Health Economics, Outcomes Research

Jazz Pharmaceuticals

. Lead global and US payer evidence strategy across marketed assets in Jazz’s neurology portfolio .

Posted 10/31/2026full-timeRemote • Pennsylvania • United StatesLead💰 $212,000 - $318,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Health Economics and Outcomes Research (HEOR) with a focus on post-marketing strategies, economic modeling, and evidence generation for biopharmaceutical products. Proven ability to collaborate with cross-functional teams and influence stakeholders while ensuring compliance with regulatory standards.

Highest-signal resume keywords

Health Economics ExpertisePost-Marketing HEOR StrategyEconomic Modeling ProficiencyCross-Functional CollaborationRegulatory Compliance Knowledge

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Economic ModelingComparative Effectiveness StudiesReal-World Evidence GenerationBudget Impact ModelingStatistical AnalysisData ValidationHealth Technology Assessment (HTA)PharmacoeconomicsEpidemiological MethodsPost-Authorization Studies

Soft Skills

Exceptional Communication SkillsInfluencing SkillsMentorship AbilitiesTeam LeadershipPresentation Skills

Tools & Technologies

Healthcare DatabasesInteractive Economic ModelsStatistical SoftwareBudget ModelsValue Dossiers

Industry Keywords

Biopharmaceutical IndustryManaged Care LandscapeRare DiseaseMarket AccessPayer EngagementHealth PolicyICERFDA GuidanceAMCP DossiersNeurology Portfolio

About the role

Key responsibilities & impact

Lead global and US payer evidence strategy across marketed assets in Jazz’s neurology portfolio
Maximize brand potential, defend value, secure expanded access, and drive post-launch evidence generation
Develop evidence strategies for label expansions, new formulations, line extensions, and expanded patient subpopulations
Partner with Medical Affairs, Clinical Development, and Biostatistics on Phase 3b/4, pragmatic, and expanded access studies
Lead rare disease registries, natural history extensions, and post-authorization safety/efficacy studies
Design comparative effectiveness, adherence, burden-of-illness, and real-world data studies
Co-create HTA reassessment strategies and analytical packages with EU/INT HEOR teams
Direct updates to Global Value Dossiers, systematic literature reviews, and meta-analyses
Lead AMCP dossiers, unbranded value summaries, and state Medicaid submission dossiers
Design and train teams on interactive economic models and reactive scientific presentations
Ensure US HEOR materials comply with FDAMA Section 114, the 21st Century Cures Act, and FDA HCEI guidance
Evaluate outcomes-based risk-sharing agreements and real-world endpoint tracking frameworks
Monitor US health policy, ICER, and value framework developments
Formulate and execute cost-effectiveness, cost-utility, budget impact, and cost-offset modeling strategies
Build and adapt economic models using mature clinical and real-world data
Serve as GVHEOR representative in IEGP governance and align evidence initiatives with brand objectives
Partner with Market Access and cross-functional teams on post-launch evidence initiatives
Lead publications, manuscripts, and conference presentations
Manage budgets, external HEOR consultancies, academic partners, and CROs
Provide mentorship and technical guidance to evidence and value generation staff

Requirements

What you’ll need

Master’s degree (MSc, MS, MPH) or PhD in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field
Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm
Extensive experience designing and executing post-marketing HEOR strategies, real-world comparative effectiveness studies, and evidence roadmaps supporting label expansions, line extensions, and value defense
Comprehensive knowledge of the US managed care landscape and global HTA environments
Proven technical expertise building, adapting, and validating economic models, including Markov, partitioned survival, microsimulation, and dynamic budget impact models
Proven track record collaborating with US Market Access, Pricing/Contracting, and Payer Field Teams to develop compliant customer-facing tools, interactive budget models, and AMCP dossiers
Demonstrated understanding of rare disease post-launch evidence challenges
Working knowledge of major US and global healthcare databases and advanced epidemiological methods
Demonstrated ability to work with regional HEOR teams, especially EU/INT
Ability to balance evidence strategy with hands-on execution of complex technical deliverables
Exceptional verbal, written, and presentation skills; ability to influence cross-functional teams and defend methodologies
Experience with neurology assets preferred
Track record leading HEOR strategy and evidence deliverables for marketed pharmaceutical products
Launch lead for at least 2 assets as US HEOR lead, or country-level HTA lead
Experience conducting post-marketing RWE, patient registry studies, and economic evaluations
Strong peer-reviewed publication record in health economics and outcomes research

Benefits

Comp & perks

Discretionary annual cash bonus or incentive compensation
Discretionary equity grants
Medical insurance
Dental insurance
Vision insurance
401k retirement savings plan
Flexible paid vacation