Senior Director, Global Medical Director – Breast Cancer

Jazz Pharmaceuticals

. Lead the Breast Cancer Global Medical functional matrix team .

Posted 11/3/2026full-timeRemote • Pennsylvania • United States, United KingdomSenior💰 $268,000 - $402,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive expertise in Medical Affairs and Clinical Development, particularly in breast cancer and HER2-targeted therapies, with a strong focus on evidence generation strategies and stakeholder engagement. Proven ability to lead cross-functional teams and navigate complex matrix organizations effectively.

Highest-signal resume keywords

Medical Affairs LeadershipEvidence Generation Strategy DevelopmentOncology Drug DevelopmentStakeholder ManagementCross-Functional Collaboration

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial DesignPublication Strategy DevelopmentEvidence Generation ActivitiesHealth Outcomes ResearchIntegrated Evidence Generation PlanTarget Product Profile DevelopmentLifecycle ManagementReal-World Evidence InitiativesAnalytic Needs IdentificationPivotal Trial Data Interpretation

Soft Skills

Strategic ThinkingOperational ExecutionInfluencing Without AuthorityEmotional IntelligenceCritical Thinking

Certifications & Qualifications

Advanced Scientific Degree (PharmD, PhD, MD, MBBS, Nurse Practitioner, PA)

Industry Keywords

Breast CancerHER2-Targeted TherapiesPharmaceutical IndustryBiotechnology IndustryClinical DevelopmentMedical AffairsMatrix OrganizationsStakeholder PerspectivesFast-Paced EnvironmentOncology Indications

About the role

Key responsibilities & impact

Lead the Breast Cancer Global Medical functional matrix team
Partner with US and EUR/INT Medical Affairs teams to understand regional customers, patients, healthcare providers, and healthcare system needs and priorities
Represent and advocate for medical perspectives within global cross-functional teams and governance forums, including CDT, LDT, PGC, and DPRC
Contribute Medical Affairs expertise to inform early development activities, including Target Product Profile development, clinical trial design, and lifecycle planning
Ensure regional needs and insights are appropriately considered in clinical development discussions, evidence-generation activities, and lifecycle planning
Maintain and apply a deep understanding of the competitive landscape to inform evidence generation strategy and internal development decisions
Lead the development, maintenance, and execution of the Integrated Evidence Generation Plan in breast cancer
Partner across Medical Affairs, Clinical Development, Regulatory Affairs, Market Access, HEOR, RWE, Commercial, and other cross-functional teams
Lead and support evidence-generation activities, including investigator-sponsored studies, real-world evidence initiatives, health outcomes research, and Phase IV interventional studies
Lead the development of the breast cancer medical narrative by identifying and advancing key analytic needs and informing interpretation of pivotal trial data
Provide Medical Affairs leadership and input into the Payor Value and Evidence Plan
Lead development and execution of publication strategy and publication plans
Support scientific communications, congress planning, advisory boards, and external engagement activities
Act as a breast cancer subject matter expert for internal cross-functional stakeholders

Requirements

What you’ll need

A minimum of 10 years of Medical Affairs, Clinical Development, or related pharmaceutical or biotechnology industry experience is required, preferably in oncology
Experience in breast cancer and/or HER2-targeted therapies are strongly preferred
Demonstrated experience developing and executing evidence-generation strategies, publication plans, and external scientific engagement activities
Strong understanding of clinical research, evidence generation, and oncology drug development
Proven ability to influence without authority and operate effectively within complex matrix organizations
Strong strategic thinking coupled with excellent operational execution skills
Excellent written, verbal, presentation, and stakeholder management skills
Ability to build productive partnerships across regions and functions and effectively represent diverse stakeholder perspectives
Demonstrated ability to manage multiple priorities and deliver high-quality outcomes in a fast-paced environment
Experience in the lifecycle management of oncology indications in breast cancer strongly desired
Evidence of success in matrix organizations and track record of high performing behaviors, including independent critical thinking, initiative, and execution under time pressure with competing priorities
Self-awareness and emotional intelligence as demonstrated by prior experience navigating complex matrix environments successfully
Advanced scientific or healthcare degree required (PharmD, PhD, MD, MBBS, Nurse Practitioner, PA, or equivalent)

Benefits

Comp & perks

Discretionary annual cash bonus or incentive compensation
Discretionary equity grants
Medical insurance
Dental insurance
Vision insurance
401k retirement savings plan
Flexible paid vacation