Director, Clinical Pharmacology

Johnson & Johnson

. Develop and/or oversee compound-specific Clinical Pharmacology strategy across all stages of development .

Posted 11/5/2026full-timeUnited StatesLead💰 $168,000 - $290,950 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in Clinical Pharmacology strategy, including PK, PD, and model-informed drug development principles. Proven ability to lead cross-functional teams, mentor colleagues, and ensure compliance with regulatory requirements.

Highest-signal resume keywords

PhD In Pharmaceutical Sciences10+ Years Experience In Pharmaceutical IndustryExpert Knowledge Of PK, PD, PK-PDAdvanced Analysis Methods (Population Analysis, PBPK, QSP)Leadership And Team Development

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Clinical Pharmacology Strategy DevelopmentClinical Study DesignNon-Compartmental AnalysisPopulation ModelingSimulation AnalysisDrug Development Process UnderstandingRegulatory Document PreparationTherapeutic Area ExpertiseProduct Differentiation StrategiesScientific Publication And Presentation

Soft Skills

Excellent Communication SkillsMentoring And CoachingTeam LeadershipCollaborationInterpersonal Skills

Tools & Technologies

NONMEMRGastroplusSimcypWinnonlinMatlab

Industry Keywords

Clinical PharmacologyTranslational MedicineModel Informed Drug Development (MIDD)Regulatory RequirementsPharmaceutical R&D ProcessTherapeutic LandscapeDrug InteractionsPatient Population UnderstandingSOP ComplianceBusiness Development Opportunities

About the role

Key responsibilities & impact

Develop and/or oversee compound-specific Clinical Pharmacology strategy across all stages of development
Lead clinical pharmacology strategy on Compound Development Teams and provide recommendations affecting drug development decisions
Design clinical pharmacology studies and clinical pharmacology components of clinical studies
Apply PK, PD, PK-PD, translational medicine, and model-informed drug development principles
Integrate nonclinical data, PK/PD, patient characteristics, disease states, competitive landscape, and drug interactions to support go/no-go decisions, dose selection, patient sub-population support, and study design
Plan, conduct, interpret, and oversee non-compartmental, population, modeling, and simulation analyses
Provide regulatory input for clinical pharmacology strategy, interactions, labeling, clinical use, and regulatory documents
Represent Clinical Pharmacology and Pharmacometrics in cross-functional teams, initiatives, governance meetings, and external regulatory meetings
Manage a team of CPP colleagues and provide oversight, guidance, mentoring, and career development
Supervise operational elements of CPP studies and ensure compliance with SOPs, regulations, and Johnson & Johnson Credo principles
Develop product differentiation strategies based on compound attributes and therapeutic landscape
Evaluate business development opportunities and provide recommendations
Contribute to scientific and technical advancement through publications, presentations, professional societies, external collaborations, and industry engagement
Develop therapeutic area expertise and relationships with internal and external partners
Ensure accountability for Clinical Pharmacology deliverables, timelines, and project goals

Requirements

What you’ll need

A PhD in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, or relevant Biological Sciences is required
10+ years of experience in the pharmaceutical industry is required
Expert knowledge and understanding of PK, PD, PK-PD, and/or Translational Medicine and their applications in model informed drug development (MIDD) is required
Understanding of advanced analysis methods (e.g., population analysis, PBPK, QSP) and modeling tools (e.g., NONMEM, R, Gastroplus, Simcyp, Winnonlin, Matlab) is required
Detailed understanding of overall process of drug development including MIDD and the overall pharmaceutical R&D process is required
Drug development experience in one or multiple therapeutic areas, including understanding of disease, patient population, and treatment paradigms, is required
Detailed understanding of US, European, and Asian regulatory requirements and guidelines is required
Excellent communication skills, leading meetings and interacting with team members, collaborators, and regulatory authorities, is required
Experience leading a team, developing talent, and providing feedback, coaching, and career development to direct reports is required
Outstanding leadership and ability to mentor junior colleagues is required
Strong level of expertise and scientific reputation through multiple publications and presentations is preferred
Up to 5% international or domestic travel may be required

Benefits

Comp & perks

Company consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation – 120 hours per calendar year
Sick time – 40 hours per calendar year
Holiday pay, including Floating Holidays – 13 days per calendar year
Work, Personal and Family Time – up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year
Inclusive interview process accommodations
Up to 5% international or domestic travel may be required