Principal Scientist – Data Science, AI & Generative AI Systems – R&D

Johnson & Johnson

. Design, build, test, and deploy AI solutions for documentation, knowledge retrieval, evidence synthesis, and decision support in the TDS ecosystem .

Posted 10/16/2026full-timeSpring House • Pennsylvania • United StatesLead💰 $117,000 - $201,250 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in designing and deploying AI solutions, particularly in regulated environments, while applying responsible AI practices and collaborating with diverse stakeholders. Proficient in building agentic AI workflows and maintaining software engineering standards.

Highest-signal resume keywords

AI Solution DevelopmentLarge Language Models (LLMs)Python ProgrammingPharmaceutical Product DevelopmentResponsible AI Practices

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

AI DevelopmentNLP SolutionsGenerative AIModel EvaluationModular DesignTestingDocumentationLifecycle ManagementRetrieval-Augmented GenerationEmbeddings

Soft Skills

Strong Communication Skills

Tools & Technologies

LangGraphDSPyMem0Vector Databases

Industry Keywords

Regulated EnvironmentsGxPChemistryManufacturing and Controls (CMC)AI GovernanceContent Safety

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Design, build, test, and deploy AI solutions for documentation, knowledge retrieval, evidence synthesis, and decision support in the TDS ecosystem
Build agentic AI workflows coordinating models, tools, data, and human review across multi-step scientific and supply chain processes
Develop reusable AI capabilities aligned with DDSAI AI/ML architecture and platform standards
Translate scientific, regulatory, and operational needs into scalable AI systems for regulated environments
Establish evaluation frameworks for LLM systems, including rubrics, traceability, robustness, uncertainty, and usability
Apply responsible AI practices, including human-in-the-loop validation, risk assessment, content safety, and governance
Maintain software engineering practices including modular design, testing, documentation, and lifecycle management
Contribute to best practices for LLM, RAG, and agentic AI systems across DDSAI and TDS
Partner with regulatory, quality, CMC, scientific, and technical stakeholders to define use cases, validate outputs, and drive adoption
Collaborate with DDSAI AI/ML on infrastructure, architecture, evaluation, and reusable components
Communicate system behavior, risks, and tradeoffs to technical and non-technical stakeholders

Requirements

What you’ll need

Degree in Engineering, Data Science, Life Sciences, Computer Science, or related field
3–5+ years of hands-on experience building and deploying AI, NLP, or generative AI solutions, including large language models (LLMs)
Experience in Pharmaceutical Product Development, including Chemistry, Manufacturing and Controls (CMC)
Strong proficiency in Python
Strong communication skills, with the ability to explain technical topics to non-technical stakeholders
Experience with open-source agentic frameworks such as LangGraph, DSPy, or mem0 (preferred)
Experience with retrieval-augmented generation, embeddings, vector databases, and model evaluation (preferred)
Exposure to regulated environments (GxP) (preferred)
Familiarity with responsible AI frameworks, content safety practices, and AI governance in regulated environments (preferred)

Benefits

Comp & perks

Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation – 120 hours per calendar year
Sick time – 40 hours per calendar year; 48 hours for Colorado residents; 56 hours for Washington residents
Holiday pay, including Floating Holidays – 13 days per calendar year
Work, Personal and Family Time – up to 40 hours per calendar year
Parental Leave – 480 hours within one year of birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year