Principal Scientist, R&D – Orthopedics, Growth Factors

Johnson & Johnson

. Serve as the primary subject matter expert and technical point of contact for the CG BIO partnership .

Posted 9/15/2026full-timeWest Chester • Massachusetts • United StatesLead💰 $117,000 - $201,250 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Biomedical Engineering and advanced bone graft substitutes, with a strong focus on regulatory strategies and technical education for medical professionals. Proven ability to translate complex user needs into actionable specifications while leading cross-functional collaborations.

Highest-signal resume keywords

Ph.D. Or Master Of Science In Biomedical Engineering8+ Years R&D Or Technical Leadership ExperienceExpertise In Growth Factors And Osteoinductive MaterialsStrong Knowledge Of US Regulatory Landscape For BiologicsExperience In Spine Or Orthopedic Trauma Spaces

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Technical Point Of ContactProduct Lifecycle ManagementBiochemical And Biomechanical Data AnalysisRegulatory Submission SupportTechnical Training Module DevelopmentSurgical Workflow UnderstandingHandling Characteristics OptimizationPharmacokinetic Release Profile ImprovementCollagen Sponges And Synthetic Putties ExpertiseWhite Paper And Scientific Publication Authoring

Soft Skills

Technical CollaborationCustomer Feedback GatheringEducational Material DevelopmentEngagement With KOLs And SurgeonsPresentation Skills

Industry Keywords

Medical DeviceBiotechnologyPharmaceuticalsRegulatory LandscapeBiologicsCombination ProductsBLAPMA510(k)HCT/P

About the role

Key responsibilities & impact

Serve as the primary subject matter expert and technical point of contact for the CG BIO partnership
Lead technical activities and decisions between external R&D teams and internal DePuy Synthes teams
Support initial global launches and product lifecycle management
Optimize and improve Novosis formulations and procedural kits
Ensure handling characteristics, release kinetics, and bioactivity meet global spine and trauma market needs
Translate orthopedic and neurosurgeon user needs into actionable technical specifications
Lead brainstorming and technical collaborations to develop priority concepts
Develop pre-clinical, clinical, regulatory, and reimbursement strategies
Act as the primary subject matter expert on rhBMP-2 and advanced bone graft substitutes
Develop technical training modules and educational materials for global sales and marketing teams
Engage KOLs, spine surgeons, and trauma specialists through technical education and surgical training labs
Gather customer feedback and present at global technical conferences
Partner with Medical Affairs, HEMA, and Clinical teams on evidence generation strategies
Analyze biochemical and biomechanical data for marketing collateral
Author white papers, scientific publications, and technical reports

Requirements

What you’ll need

Advanced degree (Ph.D. or Master of Science) in Biomedical Engineering, Materials Science, Molecular Biology, or a closely related highly technical discipline
Minimum of 8 years of progressive R&D or technical leadership experience within the medical device, biotechnology, or pharmaceuticals sector
Documented expertise in growth factors and osteoinductive materials
Experience working directly within the spine or orthopedic trauma spaces
Understanding of surgical workflows, fusion criteria, and bone healing biology
Proven track record working with carrier materials, including collagen sponges, synthetic putties, and granules
Experience improving handling characteristics or pharmacokinetic release profiles
Demonstrated success educating and partnering with surgeons
Strong working knowledge of the US regulatory landscape for biologics and combination products, including BLA, PMA, 510(k), and HCT/P
Experience supporting regulatory submissions to the FDA

Benefits

Comp & perks

Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation – 120 hours per calendar year
Sick time – 40 hours per calendar year
Holiday pay, including Floating Holidays – 13 days per calendar year
Work, Personal and Family Time – up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year
Employee accommodation support for applicants with disabilities