Senior Director, Immunology – AI Systems

Johnson & Johnson

. Define and maintain the Immunology AI strategy and multi-year roadmap .

Posted 11/7/2026full-timeRemote • United StatesSenior💰 $204,000 - $351,900 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in defining and executing AI strategies within the pharmaceutical R&D landscape, with a strong focus on data governance, technical leadership, and stakeholder alignment. Proven ability to lead high-performing teams and drive organizational change through the adoption of AI and data literacy.

Highest-signal resume keywords

AI/ML Strategy DevelopmentData EngineeringLeadership in Pharmaceutical R&DGovernance and Portfolio ManagementExecutive Communication

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

AI/MLData ProductsAnalytics PlatformsKnowledge RepresentationBiomedical Data AnalysisPortfolio Management PracticesModel ValidationData PrivacyRisk ManagementChange Management

Soft Skills

Strategic ThinkingDecision FramingInfluence in Matrixed OrganizationsTalent DevelopmentCommunication Skills

Tools & Technologies

CDISCGA4GHFHIRNCI ThesaurusKnowledge GraphsData Catalogs

Industry Keywords

Life SciencesHealthcarePharmaceuticalBiotechnologyImmunology R&D

About the role

Key responsibilities & impact

Define and maintain the Immunology AI strategy and multi-year roadmap
Lead strategic portfolio planning, including opportunity identification, value framing, prioritization, sequencing, investment choices, dependencies, and resource alignment
Create an integrated execution model with decision rights, accountable owners, milestones, risks, and value measures
Partner with Immunology scientific and development leaders across discovery, translational research, clinical development, biomarkers, evidence generation, and portfolio decision-making
Provide technical leadership on AI solution design, data readiness, model suitability, validation, scalability, interoperability, and responsible use
Orchestrate alignment and delivery across DDSAI, J&J Technology, Immunology Therapeutic Area, Global Development, and Global Regulatory Affairs
Ensure fit-for-purpose data foundations, including reusable data products, metadata, ontologies, knowledge graphs, catalogs, and access pathways
Establish portfolio governance and stage-gate decision processes from experimentation through production, scale, operations, and lifecycle management
Define portfolio success measures, including scientific and business outcomes, adoption, time or quality improvements, scalability, reuse, and return on investment
Drive adoption and organizational change by embedding AI into scientific and development workflows and advancing AI and data literacy
Build internal and external partnerships and determine when to build, buy, partner, or reuse enterprise solutions
Lead, develop, and retain a high-performing team spanning AI strategy, technical product leadership, data products, program execution, and stakeholder engagement
Represent the Immunology AI strategy with senior R&D and enterprise stakeholders, communicating progress, choices, risks, and value
Report through Research & Development Data, Data Science and AI to the Vice President, Immunology and Cardiopulmonary, DDSAI

Requirements

What you’ll need

Advanced degree (PhD, MD, PharmD, MS, or equivalent experience) in computer science, AI/ML, engineering, biomedical sciences, computational biology, applied mathematics, data science, or a related scientific or technical discipline
Minimum of 10 years of post-academic industry or equivalent experience
Leadership of complex data, digital, AI, or technology-enabled life sciences initiatives
Experience defining strategy and translating it into a prioritized roadmap and coordinated execution plan across complex multistakeholder ecosystems
Strong technical fluency in AI/ML, data engineering, data products, analytics platforms, knowledge representation, and solution lifecycles
Experience with complex, high-dimensional biomedical data, including omics, imaging, translational, clinical trial, biomarker, competitive intelligence, and real-world data
Ability to lead through influence in a matrixed pharmaceutical organization, align senior stakeholders, resolve ambiguity, and drive decisions across organizational boundaries
Experience establishing governance, operating models, portfolio management practices, and value-tracking mechanisms for AI, data, digital, or technology portfolios in pharmaceutical R&D
Strong people leadership and talent-development experience
Excellent executive communication, strategic thinking, synthesis, and decision-framing skills
Preferred: life sciences, healthcare, pharmaceutical, biotechnology, or medical technology experience; Immunology R&D experience
Preferred: enterprise or therapeutic-area AI strategy and execution across discovery and development workflows
Preferred: technical product management, agile delivery, change management, and scaled adoption of AI-enabled products
Preferred: responsible AI, model validation, data privacy, security, regulatory expectations, and risk management in a biomedical environment
Preferred: CDISC, GA4GH, FHIR, NCI Thesaurus, ontologies, knowledge graphs, and data catalogs
Preferred: build-versus-buy-versus-partner evaluation and strategic technology or external innovation partnerships

Benefits

Comp & perks

Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation – 120 hours per calendar year
Sick time – 40 hours per calendar year; 48 hours for Colorado employees; 56 hours for Washington employees
Holiday pay, including Floating Holidays – 13 days per calendar year
Work, Personal and Family Time – up to 40 hours per calendar year
Parental Leave – 480 hours within one year of birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year