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Johnson & Johnson

Senior Director, Integrative Biology – Oncology Discovery

Johnson & Johnson

. Define and execute the computational biology strategy for Oncology Discovery across therapeutic modalities .

Posted 11/4/2026full-timeUnited StatesSenior💰 $204,000 - $351,900 per yearWebsite

Core Competencies

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Core Competencies

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Demonstrates expertise in Computational Biology and Oncology Discovery, with a strong focus on integrating multi-omics data and applying machine learning techniques to drive impactful scientific discoveries. Proven leadership in mentoring teams and collaborating across multidisciplinary functions to advance cancer research.

Highest-signal resume keywords
Ph.D. In Computational BiologyDeep Expertise In Cancer BiologyComputational Biology Leadership ExperienceStatistical And Computational Methods ExpertiseMulti-Omics Data Analysis

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Computational BiologyBioinformaticsMachine LearningPredictive ModelingStatistical MethodsMulti-Omics Data IntegrationBiomarker Hypothesis DevelopmentTarget IdentificationDisease SegmentationMechanism-Of-Action Understanding
Soft Skills
LeadershipMentoringCommunicationCollaborationStrategic Thinking
Tools & Technologies
AI/MLData ScienceFunctional GenomicsNetwork BiologyComputational Resources
Industry Keywords
Oncology DiscoveryCancer GenomicsTranslational ResearchPrecision MedicineDrug Discovery

About the role

Key responsibilities & impact
  • Define and execute the computational biology strategy for Oncology Discovery across therapeutic modalities
  • Lead computational approaches for target identification and validation, disease segmentation, mechanism-of-action understanding, and biomarker hypotheses
  • Integrate human tumor, patient-derived, multi-omics, and functional genomics data
  • Advance machine learning, AI, network biology, predictive modeling, and multimodal data integration
  • Partner with data science, AI/ML, informatics, and technology teams on scalable analytical approaches
  • Ensure rigorous, reproducible, interpretable computational science produces biologically meaningful hypotheses
  • Embed computational thinking and AI in discovery programs and inform experimental and portfolio decisions
  • Establish evidence frameworks for targets and therapeutic hypotheses
  • Communicate computational findings to Discovery teams and senior leadership
  • Recruit, lead, mentor, and develop computational biologists
  • Establish priorities and deploy computational resources against high-impact scientific questions
  • Build partnerships across Oncology Discovery, Translational Research, Data Science, AI/ML, Precision Medicine, and other R&D functions
  • Maintain awareness of advances in cancer genomics, functional genomics, single-cell and spatial biology, computational biology, AI/ML, and drug discovery
  • Establish external collaborations and represent the organization at conferences, through publications, and in external scientific interactions

Requirements

What you’ll need
  • Ph.D. or equivalent advanced degree in Computational Biology, Bioinformatics, Systems Biology, Genetics/Genomics, Biostatistics, Data Science, or a related discipline
  • Deep expertise in cancer biology and oncology drug discovery
  • 12+ years of relevant industry experience
  • Significant computational biology leadership experience with a track record of scientific impact, team development, and influence across multidisciplinary discovery teams
  • Demonstrated expertise applying statistical and computational methods to complex genomics and multi-omics data
  • Ability to translate results into testable biological hypotheses and clear recommendations for experimental scientists and senior decision-makers

Benefits

Comp & perks
  • Annual bonus with set target (% of pay) depending on pay grade / location
  • Vacation days
  • Parental leave for a minimum of 12 weeks
  • Bereavement leave
  • Caregiver leave
  • Volunteer leave
  • Well-being reimbursement
  • Programs for financial, physical and mental health
  • Service anniversary and recognition awards
  • Insurance plans for employees and, in some locations, eligible dependents