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Johnson & Johnson

Senior Director, Integrative Biology – Oncology Discovery

Johnson & Johnson

. Define and execute the computational biology strategy for Oncology Discovery across therapeutic modalities .

Posted 11/4/2026full-timeUnited StatesSeniorWebsite

Core Competencies

Role fit
Core Competencies

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Expertise in Computational Biology and Oncology Drug Discovery, with a strong focus on integrating multi-omics data and applying machine learning techniques to drive target identification and validation. Proven leadership in mentoring teams and collaborating across multidisciplinary research functions to advance scientific discovery.

Highest-signal resume keywords
Ph.D. In Computational BiologyCancer Biology ExpertiseComputational Biology LeadershipStatistical And Computational MethodsMachine Learning And AI Applications

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills
Computational BiologyBioinformaticsMulti-Omics Data IntegrationPredictive ModelingStatistical AnalysisTarget IdentificationBiomarker Hypothesis DevelopmentDisease SegmentationMechanism-Of-Action UnderstandingFunctional Genomics
Soft Skills
LeadershipMentoringCommunicationCollaborationStrategic Thinking
Tools & Technologies
AI/ML TechniquesData Science ToolsComputational ResourcesAnalytical ApproachesEvidence Frameworks
Industry Keywords
Oncology DiscoveryTranslational ResearchPrecision MedicineCancer GenomicsSingle-Cell BiologySpatial BiologyDrug Discovery

About the role

Key responsibilities & impact
  • Define and execute the computational biology strategy for Oncology Discovery across therapeutic modalities
  • Lead computational approaches for target identification and validation, disease segmentation, mechanism-of-action understanding, and biomarker hypotheses
  • Integrate human tumor, patient-derived, multi-omics, and functional genomics data
  • Advance machine learning, AI, network biology, predictive modeling, and multimodal data integration
  • Partner with data science, AI/ML, informatics, and technology teams on scalable analytical approaches
  • Embed computational thinking and AI early in discovery programs
  • Establish evidence frameworks for evaluating targets and therapeutic hypotheses
  • Communicate computational findings to Discovery teams and senior leadership
  • Recruit, lead, mentor, and develop computational biologists
  • Establish priorities and deploy computational resources against high-impact scientific questions
  • Build partnerships across Oncology Discovery, Translational Research, Data Science, AI/ML, Precision Medicine, and other R&D functions
  • Maintain awareness of advances in cancer genomics, functional genomics, single-cell and spatial biology, computational biology, AI/ML, and drug discovery
  • Establish external collaborations and represent the organization at conferences, through publications, and other scientific interactions

Requirements

What you’ll need
  • Ph.D. or equivalent advanced degree in Computational Biology, Bioinformatics, Systems Biology, Genetics/Genomics, Biostatistics, Data Science, or a related discipline
  • Deep expertise in cancer biology and oncology drug discovery
  • 12+ years of relevant industry experience
  • Significant computational biology leadership experience with a track record of scientific impact, team development, and influence across multidisciplinary discovery teams
  • Demonstrated expertise applying statistical and computational methods to complex genomics and multi-omics data
  • Ability to translate computational results into testable biological hypotheses and clear recommendations for experimental scientists and senior decision-makers

Benefits

Comp & perks
  • Inclusive work environment
  • Employee respect, diversity, dignity, and merit