Senior Principal Scientist, Biostatistics

Johnson & Johnson

. Lead major portions of biostatistical research and development projects independently .

Posted 11/11/2026full-timeUnited StatesSenior💰 $140,000 - $241,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates advanced statistical expertise in biostatistical research and development, with proficiency in R and SAS for data analysis and visualization. Capable of leading innovative methodologies, mentoring teams, and ensuring compliance with regulatory standards in pharmaceutical research.

Highest-signal resume keywords

Master’s Degree In StatisticsPhD In StatisticsAdvanced Data Analytics ExpertiseFull Proficiency In R And SASKnowledge Of Statistical Methodologies

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Biostatistical ResearchExperimental DesignStatistical AnalysisData VisualizationStatistical MethodologiesQuantitative Decision-MakingRegulatory ComplianceStatistical CommunicationsData IntegrityHealth Authority Standards

Soft Skills

Credo-Based LeadershipStrong Communication SkillsMentoring Emerging LeadersCollaborationProblem-Solving

Tools & Technologies

RSASComputational ToolsInteractive Graphical ToolsArtificial Intelligence

Industry Keywords

Pharmaceutical Research And DevelopmentTherapeutic AreasGxP ActivitiesClinical Data AnalysisCross-Pharma Consortia

About the role

Key responsibilities & impact

Lead major portions of biostatistical research and development projects independently
Apply advanced statistical expertise to experimental design, modeling, analysis planning and execution, interpretation, and statistical communications
Analyze and visualize study, experiment, or trial data
Identify and solve scientific, statistical, regulatory, operational, and partnership complexities
Lead innovative statistical methodologies and business process improvements
Guide study and trial design optimization
Support strategic scenario planning, quantitative decision-making, and regulatory activities
Collaborate cross-functionally to identify and resolve issues
Serve as point of contact for project or program deliverables
Represent Statistics & Decision Sciences on development teams, working groups, senior management reviews, and health authority interactions
Build partnerships with internal colleagues, CROs, consultants, and other external partners
Drive statistical methodology advancement through scholarly publications and presentations
Participate in professional organizations, cross-pharma consortia, and industry standards development
Author scientific journal manuscripts and peer review or edit professional journal manuscripts
Supervise contractors, special assignment personnel, interns, or co-ops as required
Mentor emerging leaders in techniques, processes, and responsibilities
Ensure quality, timeliness, compliance, and adherence to project and company standards

Requirements

What you’ll need

Master’s Degree in Statistics with 10+ years experience OR PhD in Statistics with 7+ years in related clinical data analysis experience
Credo-based leadership consistent with J&J IM Leadership Imperatives
Advanced data analytics expertise grounded in statistical principles
Full proficiency in R and SAS
Familiarity with computational tools, innovative data-adaptive methods, and artificial intelligence
Knowledge of statistical methodologies, drug development, pharmaceutical research and development, and health authority standards
Experience across multiple disease areas/targets within or across Therapeutic Areas
Strong written, oral, and interpersonal communication skills
Ability to translate intricate statistical concepts for non-statisticians
Proficiency communicating statistical findings using interactive graphical tools
Understanding of regulatory guidance, GxP activities, Data Integrity, and company standard operating procedures
Ability to supervise contractors, special assignment personnel, interns, or co-ops as required
Ability to mentor emerging leaders
Ability to comply with project and company standards and deliverables

Benefits

Comp & perks

Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation –120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
Holiday pay, including Floating Holidays –13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year