Regional Business Director

Karyopharm Therapeutics Inc.

. Provide leadership and direction to field sales representatives to achieve company objectives, meet customer needs, foster team development, and drive sales of XPOVIO within approved indications .

Posted 10/23/2026full-timeRemote • United StatesLead💰 $230,000 - $260,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates strong leadership in field sales management, with a focus on driving sales performance and team development within the pharmaceutical industry. Possesses extensive knowledge of oncology and rare diseases, along with the ability to execute commercial initiatives and foster key relationships.

Highest-signal resume keywords

Pharmaceutical Sales ExperienceField Sales ManagementOncology ExpertiseTeam DevelopmentBudget Management

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Sales PlanningMarket AnalysisCompliance OversightTraining and CoachingPerformance Recognition

Soft Skills

LeadershipCollaborationCommunicationTalent RecruitmentRelationship Building

Industry Keywords

PharmaceuticalsOncologyRare DiseaseManaged CareKaryopharm ICARE Values

About the role

Key responsibilities & impact

Provide leadership and direction to field sales representatives to achieve company objectives, meet customer needs, foster team development, and drive sales of XPOVIO within approved indications
Develop field sales plans and lead a regional team of field sales representatives
Allocate the regional sales budget and control expenses to meet or exceed business objectives
Coordinate with Market Access and Medical Affairs at the regional level
Analyze market drivers and business dynamics and provide cross-functional insights
Teach, train, and coach sales professionals on product and disease-state knowledge
Identify training needs and communicate them to the sales training team
Ensure execution of commercial initiatives at the field level
Recognize outstanding performance and address behaviors needing improvement
Travel with sales representatives to key accounts as needed
Identify, recruit, and retain top talent for vacant sales positions
Collaborate with Sales Training to design launch-meeting, plan-of-action, and other sales training and planning programs
Foster relationships with Key Opinion Leaders, MD networks, and other industry contacts
Oversee field sales team compliance with company policies and legal and regulatory guidelines
Collaborate with the brand team by providing field-level insights to influence and drive brand strategy
Report to the Vice President, US Sales

Requirements

What you’ll need

Bachelor’s degree, required
8+ years of pharmaceutical sales experience
2+ years of pharmaceutical field sales management experience at a regional level preferred
Significant experience within oncology or rare disease, including product launch(es)
Solid knowledge of retail, hospital, and managed care environments
Ability to understand and live Karyopharm’s ICARE values
Ability to travel with sales representatives to key accounts as needed

Benefits

Comp & perks

Comprehensive medical, dental, vision, disability, and life insurance
Deductible paid by KPTI
Parental leave
Matching 401(k) program with immediate vesting
Employee Stock Purchase Plan (ESPP)
Tuition reimbursement
Equity offerings, including RSUs at time of offer and annual awards
Potential annual target bonuses
Wellness program with a monthly stipend
Generous paid time off and holidays
Management development and mentoring programs
Reward and recognition programs
Cell phone allowance
Flexible work arrangements, including onsite, from home, or anywhere in between
Employee engagement, diversity, and inclusion culture