Regional Business Director

Karyopharm Therapeutics Inc.

. Develop field sales plans and lead a regional team of field sales representatives .

Posted 10/23/2026full-timeRemote • United StatesLead💰 $230,000 - $260,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive experience in pharmaceutical sales management, particularly in oncology or rare disease, with a strong focus on team leadership, training, and compliance with regulatory guidelines. Proven ability to develop and execute field sales strategies while fostering relationships with key industry stakeholders.

Highest-signal resume keywords

Pharmaceutical Sales ManagementOncology ExperienceField Sales Strategy DevelopmentTeam Leadership and TrainingRegulatory Compliance

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Sales PlanningBudget AllocationMarket Access CoordinationProduct Launch ExperienceSales Training Needs Assessment

Soft Skills

CoachingRelationship BuildingPerformance RecognitionCommunication

Industry Keywords

Pharmaceutical SalesManaged CareRetail EnvironmentHospital EnvironmentKey Opinion Leaders

About the role

Key responsibilities & impact

Develop field sales plans and lead a regional team of field sales representatives
Allocate the total regional sales budget and control expenses to meet or exceed business objectives
Coordinate with Market Access and Medical Affairs at the regional level
Provide cross-functional insights into key market drivers and business dynamics
Teach, train, and coach sales professionals on product and disease-state knowledge
Identify training needs and communicate them to the sales training team
Ensure execution of commercial initiatives at the field level
Recognize outstanding performance and address behaviors requiring improvement
Travel with sales representatives to key accounts as needed
Identify, recruit, and retain top talent for vacant sales positions
Collaborate with sales training to design programs for launch meetings, plans of action, and sales training and planning meetings
Foster relationships with Key Opinion Leaders, MD networks, and other industry contacts
Oversee field sales team compliance with company policies and legal and regulatory guidelines
Collaborate with the brand team to provide field-level insights and influence brand strategy
Report to the Vice President, US Sales
Drive sales of XPOVIO within approved indications

Requirements

What you’ll need

Bachelor’s degree, required
8+ years of pharmaceutical sales experience
2+ years of pharmaceutical field sales management experience at a regional level preferred
Significant experience within oncology or rare disease, including product launch(es)
Solid knowledge of retail, hospital, and managed care environments
Ability to understand and live Karyopharm’s ICARE values
Ability to travel with sales representatives to key accounts, as needed

Benefits

Comp & perks

Comprehensive medical, dental, vision, disability, and life insurance
Deductible paid by KPTI
Parental leave
Matching 401(k) program with immediate vesting
Employee Stock Purchase Plan (ESPP)
Equity offerings, including RSUs at time of offer and annual awards
Potential annual target bonuses
Tuition reimbursement
Wellness program with a monthly stipend
Generous PTO and holidays
Management development and mentoring programs
Reward and recognition programs
Cell phone allowance
Flexible work arrangements, including onsite, from home, or anywhere in between
Supportive, employee-engaged, diverse, and inclusive culture