Regional Director, Clinical Operations

M3 USA

. Lead, coach, and develop Site Directors and Site Managers .

Posted 10/30/2026full-timeRemote • California • United StatesLead💰 $130,000 - $160,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in clinical research operations, team leadership, and financial management, with a strong focus on compliance with FDA regulations and ICH-GCP standards. Proven ability to enhance site performance through effective coaching, strategic planning, and data-driven decision-making.

Highest-signal resume keywords

Clinical Research Operations ManagementTeam Leadership and DevelopmentFDA Regulations and ICH-GCP KnowledgeFinancial Management and BudgetingData-Driven Decision Making

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical ResearchSite Operations ManagementPerformance Metrics MonitoringBudgeting and ForecastingProtocol ComplianceRisk IdentificationEnrollment Strategy DevelopmentAudit ReadinessInvestigational Product HandlingPeople Management

Soft Skills

Strong CommunicationRelationship BuildingCoaching and MentoringProblem SolvingCollaboration

Industry Keywords

Clinical TrialsTherapeutic AreasMulti-Site NetworksSite Management OrganizationsClinical AffairsPatient CarePhysician CollaborationSafety ReportingOperational ReportsPerformance Reviews

About the role

Key responsibilities & impact

Lead, coach, and develop Site Directors and Site Managers
Set clear goals, KPIs, and expectations
Step in as Interim Site Director, or arrange coverage, when a site is in transition
Monitor site operations and performance metrics to improve efficiency, quality, enrollment, and protocol compliance
Roll out network-wide processes, systems, and SOPs consistently across sites
Partner with site leadership on budgeting, forecasting, FTE planning, and margin management
Review financial and operational reports to identify risks and trends
Work with Marketing and Participant Recruitment to strengthen enrollment strategy and forecasting
Support Business Development with feasibility input and site capability assessments
Work with Quality, Regulatory, and Clinical Affairs on audit readiness and PI oversight
Build relationships with principal investigators and serve as the regional escalation point for investigator and sponsor concerns
Support hiring, onboarding, and staffing decisions for site-level teams
Lead mid-year and annual performance reviews for direct reports

Requirements

What you’ll need

Bachelor’s degree in science, nursing, or a related field (equivalent combination of education, experience, and training considered)
7–10+ years of progressively responsible experience in clinical research or related operations
Prior experience managing teams or site operations
5+ years of people management preferred
Clinical experience across two or more therapeutic areas
Experience with multi-site networks, SMOs, TMOs, or hospital-owned physician networks preferred
Strong knowledge of FDA regulations, ICH-GCP, safety reporting, and investigational product handling
Healthcare background in a line of business with direct patient care and physician collaboration
Comfortable making financially sound, defensible business decisions
Strong communication across sites, sponsors, CROs, and regulators
Data-driven, with a track record of developing and coaching talent

Benefits

Comp & perks

401(k)
401(k) matching
Dental insurance
Disability insurance
Employee assistance program
Flexible spending account
Health insurance
Life insurance
Paid time off
Vision insurance
Remote work arrangement
Up to 50% travel opportunity