Staff Software Engineer

Natera

. Lead the design, development, and maintenance of the LIMS application and related software .

Posted 11/4/2026full-timeRemote • United StatesLead💰 $152,100 - $190,100 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive experience in leading the design and development of LIMS applications, with a strong focus on Java and Python programming, as well as expertise in relational databases and web services. Proven ability to integrate enterprise systems and improve development processes in regulated environments.

Highest-signal resume keywords

Java Application DevelopmentPython ProgrammingRelational Database ManagementWeb Services (REST)LIMS Platform Expertise

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

JavaPythonPostgreSQLMySQLJavaScriptTypeScriptREST APIsSQL ProgrammingFastAPIInfrastructure-as-Code

Soft Skills

Team LeadershipStakeholder CollaborationDesign Solutions

Tools & Technologies

DockerTerraformKafkaSQS/SNSPub/Sub

Industry Keywords

CLIA/CAPHIPAA21 CFR Part 11ISO 13485IEC 62304GxPSoftware Validation Practices

Tech Stack

Tools & technologies

AngularDockerJavaJavaScriptKafkaMySQLPostgresPythonReactSQLTerraformTypeScript

About the role

Key responsibilities & impact

Lead the design, development, and maintenance of the LIMS application and related software
Serve as a primary technical lead for the Software Engineering group
Provide design solutions and general team leadership to engineers and Technical Product Managers
Work closely with stakeholders and users to define requirements
Translate requirements into reliable, extensible, operations-friendly Java applications
Make key design and technical implementation decisions with the engineering team
Maintain a holistic view of processes and systems involved in taking patient samples from order to result in a multi-product clinical laboratory
Understand LIMS platform features and propose solutions with trade-off analysis
Leverage off-the-shelf or existing functionality when possible
Integrate enterprise systems and services to create seamless business processes
Improve development processes and procedures and evangelize best practices
Develop and maintain automated tests
Provide second-tier production support

Requirements

What you’ll need

BS degree in computer science, comparable program, or equivalent
10+ years of overall software development experience, preferably building complex data or process management applications in production
10+ years of experience with Python
10+ years of experience with web services (REST, etc.) and relational databases
Experience with front-end web programming, preferably with modern JavaScript frameworks such as React or Angular
Experience in regulated environments, including CLIA/CAP, HIPAA, 21 CFR Part 11, ISO 13485, IEC 62304, and GxP, and software validation practices
Strong relational database skills, including database design, migrations, and optimization; PostgreSQL or MySQL preferred
Demonstrated experience leading replacement or consolidation of legacy or disparate systems into a unified platform
Python skills including FastAPI, Pydantic, SQLAlchemy or similar ORM
JavaScript / TypeScript
Relational database and SQL programming
REST APIs and event-driven microservice architecture
Messaging and event streaming, including SQS/SNS, Pub/Sub, or Kafka
Infrastructure-as-code, including Terraform
Docker or container-oriented technologies

Benefits

Comp & perks

Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
Free testing for employees and their immediate families
Fertility care benefits
Pregnancy and baby bonding leave
401(k) benefits
Commuter benefits
Employee referral program
Equal Opportunity Employer committed to a diverse and inclusive workplace