Clinical Development Medical Director, MD required

Pfizer

. Provide medical and scientific expertise and oversight for one or more clinical trials .

Posted 9/25/2026full-timeUnited StatesLead💰 $239,900 - $399,800 per yearWebsite

About the role

Key responsibilities & impact

Provide medical and scientific expertise and oversight for one or more clinical trials
Serve as the single point of accountability for study design, execution, monitoring, delivery, reporting, and patient safety
Develop strategies for protocols intended to obtain worldwide compound approvals
Oversee study safety, including safety surveillance plans, individual and cumulative safety data review, SAE reporting, and benefit-risk assessments
Participate in Safety Review Teams, Data Monitoring Committees, steering committees, and other study bodies
Review literature and communicate safety information to study sites
Provide medical input into clinical development plans, protocol design, country feasibility, and study strategy
Ensure protocols, informed consent documents, and related documents meet regulatory and company requirements
Provide clinical input on monitoring guidelines, statistical analysis plans, clinical review forms, data edit checks, and data quality planning
Contribute to CRO/vendor selection and ensure medical and technical data-integrity requirements are applied
Review and interpret clinical trial efficacy and safety data
Deliver top-line reports and clinical study reports in collaboration with statisticians and medical writers
Ensure medical and scientific validity of study reports and conclusions
Disclose appropriate safety and efficacy data through ClinicalTrials.gov, EudraCT, or Pfizer.com
Provide protocol-specific training to study teams, investigators, clinical research associates, and others
Interact with healthcare professionals, regulatory authorities, key opinion leaders, and principal investigators
Monitor investigator compliance with protocol and regulatory requirements
Support issue resolution, study closeout, audit responses, and inspection readiness
Author clinical sections of regulatory documents, including Investigator Brochures, Annual Reports, IND sections, and clinical study reports
May co-author abstracts, posters, presentations, and publications
May contribute to protocol budget execution
Liaise with key opinion leaders and principal investigators to build networks for new trials

Requirements

What you’ll need

Medical degree (M.D./D.O. or equivalent)
4+ years’ work experience
Licensed by a health authority to prescribe medicines independently of supervision for at least two years after the intern/houseman year
Used the prescribing license in a patient care setting for an aggregate duration of at least one year
Ability to critically evaluate medical/scientific information
Understanding of the design, development, and execution of clinical programs and studies
Documented pharmaceutical industry experience related to clinical research programs and registration activities
Experience managing multiple studies
Ability to work standard East Coast workday hours, with occasional off-hours work
Ability to travel
Candidates must be authorized to be employed in the U.S. by any employer
Permanent work authorization in the United States required
U.S. work visa sponsorship is not available now or in the future
Preferred: documented work experience/knowledge of statistics
Preferred: training and experience in infectious diseases and/or hospital infection control
Preferred: experience with investigational clinical trials
Excellent written and oral skills
Ability to adapt to a fast-paced and changing environment
Leadership capabilities including influencing and collaborating with peers, developing and coaching others, and overseeing colleagues’ work

Benefits

Comp & perks

401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Global Performance Plan bonus target of 25.0% of base salary
Share-based long-term incentive program
Relocation assistance may be available based on business needs and/or eligibility