Clinical Pharmacology Lead

Pfizer

. Act as Clinical Pharmacology representative on Clinical Sub Teams, Development Teams, and other multifunctional teams .

Posted 9/23/2026full-timeUnited StatesSenior💰 $139,100 - $231,900 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical pharmacology, including pharmacokinetics and pharmacometrics, with a strong focus on designing and executing clinical pharmacology plans and regulatory documentation. Proven ability to lead multifunctional teams and apply innovative analytical methods to optimize drug development processes.

Highest-signal resume keywords

Clinical Pharmacology ExpertisePharmacokinetics ModelingNONMEM ExperienceRegulatory Document DevelopmentQuantitative Pharmacology Approaches

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

PharmacokineticsPharmacometricsClinical PharmacologyMechanistic PK/PD ModelingPopulation ModelingClinical Trial SimulationsDose-Range Finding StrategiesAnalytical Methods OptimizationProtocol AuthoringBiomarker Measurement Strategies

Soft Skills

Excellent Written CommunicationVerbal Communication SkillsPresentation SkillsCoaching and Mentoring

Tools & Technologies

NONMEMR

Certifications & Qualifications

M.D.Ph.D.Pharm.D.

Industry Keywords

Drug DevelopmentClinical Pharmacology PlansPK/PD AnalysesRegulatory GuidelinesSOPsFirst-in-Human StudiesMIDD PlansGlobal Meetings

About the role

Key responsibilities & impact

Act as Clinical Pharmacology representative on Clinical Sub Teams, Development Teams, and other multifunctional teams
Provide clinical pharmacology expertise, leadership, and deliverables for assigned projects
Design and execute clinical pharmacology plans and implement best practices
Ensure sufficient preclinical PK/PD knowledge for safe human administration and predictive model development before first-in-human studies
Plan and oversee project-level clinical pharmacology activities, including development plans, PK/PD analyses, and PK/immunogenicity/biomarker measurement strategies
Plan and oversee study-level activities, including protocol authoring, clinical phase oversight, and reporting
Ensure appropriate dose-range finding strategies and optimal patient doses and dosage regimens
Design and implement end-to-end MIDD plans
Apply innovative analytical methods to optimize doses, dosage regimens, and study designs
Contribute to regulatory documents, including briefing documents, regulatory queries, Investigator’s Brochures, INDs, NDAs, and MAAs
Develop new methodologies through internal and external collaborations
Coach less experienced colleagues and team members
Stay current with literature, regulatory guidelines, internal guidance, and SOPs
Influence the external environment through publications, presentations, scientific societies, and industry consortia

Requirements

What you’ll need

M.D./Ph.D., or equivalent training/experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or related discipline
Pharm.D. or equivalent training/experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or related discipline
5+ years of industry experience in clinical pharmacology and/or clinical PK/PD and/or Pharmacometrics/Systems Pharmacology
1+ year of industry experience in clinical pharmacology and/or clinical PK/PD and/or Pharmacometrics/Systems Pharmacology
Strong quantitative skills and expertise in mechanistic PK/PD modeling/systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations
Experience using NONMEM and R
Intimate knowledge of drug development
Experience applying quantitative pharmacology approaches to knowledge integration
Excellent written and verbal communication skills
Demonstrated presentation skills
Ability to attend global meetings periodically across different time zones
Must be authorized to be employed in the U.S. by any employer
Permanent work authorization in the United States required
U.S. work visa sponsorship is not available now or in the future

Benefits

Comp & perks

Global Performance Plan bonus target of 17.5% of base salary
Share-based long-term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Paid holidays
Paid personal days
Paid caregiver/parental leave
Paid medical leave
Medical, prescription drug, dental, and vision coverage
Relocation assistance may be available based on business needs and/or eligibility
Employee referral bonus eligibility