Clinical Pharmacology Lead

Pfizer

. Act as Clinical Pharmacology representative on Clinical Sub Teams, Development Teams, and other multifunctional teams .

Posted 9/23/2026full-timeUnited StatesSenior💰 $106,000 - $176,600 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical pharmacology, including mechanistic PK/PD modeling and clinical trial simulations. Proficient in designing and executing clinical pharmacology plans while ensuring compliance with regulatory standards.

Highest-signal resume keywords

Clinical Pharmacology ExpertiseMechanistic PK/PD ModelingClinical Trial SimulationsRegulatory Document ContributionExcellent Communication Skills

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

PharmacokineticsPharmacometricsPopulation ModelingNONMEMRClinical Development PlansDose-Range-Finding StrategiesAnalytical MethodsProtocol AuthoringStudy Design Optimization

Soft Skills

LeadershipCollaborationPresentation SkillsInfluencing SkillsGlobal Team Coordination

Certifications & Qualifications

M.D.Ph.D.Pharm.D.

Industry Keywords

Clinical PharmacologyPK/PD AnalysesRegulatory GuidelinesINDsNDAsMAAsSOPsLiterature Meta-AnalysesScientific SocietiesIndustry Consortia

About the role

Key responsibilities & impact

Act as Clinical Pharmacology representative on Clinical Sub Teams, Development Teams, and other multifunctional teams
Provide clinical pharmacology expertise, leadership, and deliverables for assigned projects
Design and execute clinical pharmacology plans and implement best practices on project teams
Collaborate with disciplines to establish preclinical PK/PD knowledge and predictive models before first-in-human studies
Plan and oversee project-level clinical pharmacology activities, including clinical development plans and PK/PD analyses
Plan and oversee study-level activities, including protocol authoring, clinical phase oversight, and reporting
Ensure appropriate dose-range-finding strategies and optimal doses and dosage regimens
Design and implement end-to-end model-informed drug discovery and development plans
Use innovative analytical methods to optimize doses, dosage regimens, and study designs
Contribute to regulatory documents, including briefing documents, regulatory queries, investigator brochures, INDs, and NDAs/MAAs
Monitor literature, regulatory guidelines, internal guidance, and SOPs
Influence the external environment through publications, presentations, scientific societies, and industry consortia

Requirements

What you’ll need

Strong quantitative skills and expertise in mechanistic PK/PD modeling/systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations using NONMEM, R, or similar tools
M.D./Ph.D., or equivalent training/experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or a related discipline, with 0+ years of industry experience
Pharm.D., or equivalent training/experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or a related discipline, with 2+ years of industry experience
Excellent written and verbal communication skills
Demonstrated presentation skills
Ability to work in global team meetings across different time zones periodically based on business necessity
Ability to influence and collaborate with peers to achieve meaningful outcomes and create business impact
Must be authorized to be employed in the U.S. by any employer
Must have permanent work authorization in the United States
U.S. work visa sponsorship is not available now or in the future

Benefits

Comp & perks

Global Performance Plan bonus target of 15.0% of base salary
Share-based long-term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday, and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental, and vision coverage
Relocation assistance may be available based on business needs and/or eligibility
Employee referral bonus eligibility