Director, CRC Strategy – Indication Lead

Pfizer

. Define, adapt, and drive the overall CRC commercial strategy across the 1L opportunity, BREAKWATER launch, and treatment journey .

Posted 9/24/2026full-timeUnited StatesSenior💰 $176,600 - $294,300 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in developing and executing commercial strategies, managing P&L, and leading cross-functional teams to drive measurable growth in the CRC space. Strong analytical skills and the ability to influence stakeholders are essential for success in this role.

Highest-signal resume keywords

Commercial Strategy DevelopmentP&L OwnershipCross-Functional LeadershipKPI Framework ManagementUS Marketing Experience

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Brand Strategy ExecutionForecastingKPI MeasurementAnalytical SkillsProject Leadership

Soft Skills

Influencing PeersCollaborationCoachingCommunication

Industry Keywords

CRCBRAFTOVIPatient JourneyMarket LaunchCommercial Experience

About the role

Key responsibilities & impact

Define, adapt, and drive the overall CRC commercial strategy across the 1L opportunity, BREAKWATER launch, and treatment journey
Co-own the go-to-market/promotional-field model and targeting strategy with precision-engagement and field-strategy leads
Lead cross-functional and leadership updates for the indication and represent CRC in franchise strategic planning, OP, and LE
Own CRC revenue, TRx, and NPS as the accountable indication lead
Lead the CRC KPI Measurement Framework for new-patient acquisition, leading indicators, and persistence
Support CRC forecasting, latest estimates, and phasing
Lead the CRC marketing group and hold shared accountability for delivering strategic imperatives
Partner with field sales, TLELs, Medical, Patient Services, RC, Legal, Regulatory, analytics, and agencies
Build the strategy to prevent unnecessary early BRAFTOVI discontinuation
Design proactive HCP and patient/caregiver support infrastructure
Translate early persistence and adverse-event signals into a measurable, ROI-accountable support model
Own APP strategy across the patient journey and serve as tactical plan lead for the indication
Ensure tactics align with CRC strategic imperatives and are executed with operating discipline across the matrix

Requirements

What you’ll need

Ability to influence and collaborate with peers, develop and coach others, and oversee and guide colleagues to achieve meaningful outcomes and business impact
Bachelor’s degree with 8+ years, MBA/MS with 7+ years, or PhD with 5+ years of marketing, commercial, or related experience
US marketing / commercial experience
Demonstrated ability to develop, adapt, and execute brand strategy that drives measurable growth
Ownership of a commercial P&L, forecast, or KPI framework, with strong analytical and business acumen
Strong project leadership across multiple simultaneous priorities, stakeholders, and timelines
Proven ability to lead and influence cross-functionally without direct authority
Excellent verbal and written communication, including with senior leadership
Candidates must be authorized to be employed in the U.S. by any employer
Permanent work authorization in the United States required
U.S. work visa sponsorship is not available now or in the future

Benefits

Comp & perks

Pfizer Global Performance Plan with a bonus target of 20.0% of base salary
Share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility