Director, Global Commercial Strategy – Portfolio Strategy

Pfizer

. Set the future vision for Pfizer’s Oncology portfolio and help drive impact on patients’ lives .

Posted 9/17/2026full-timeNew York City • New York • United StatesLead💰 $176,600 - $294,300 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Oncology portfolio management, commercial development, and strategic planning, with a strong ability to lead cross-functional teams and influence decision-making. Proficient in analyzing market trends and developing investment cases for early and late-stage assets.

Highest-signal resume keywords

Oncology Landscape ExpertiseCommercial Development ExperienceStrategic Planning and ExecutionCross-Functional Team LeadershipFinancial Valuation and Forecasting

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Commercial PlanningMarket AnalysisInvestment Case DevelopmentProduct Launch StrategyDecision-Making ToolsAsset Progression ManagementBusiness Proposal DevelopmentForecastingCompetitive Landscape EvaluationStrategic Scenario Planning

Soft Skills

Influencing Without AuthorityCollaborative Culture DevelopmentCoaching and MentoringHigh Sense of UrgencyLeadership of Matrix Teams

Industry Keywords

PharmaceuticalBiotechnologyMedical DeviceCommercial DevelopmentStrategy ConsultingGlobal Product LaunchEmerging TrendsRegulatory ComplianceMarket AccessCross-Functional Collaboration

About the role

Key responsibilities & impact

Set the future vision for Pfizer’s Oncology portfolio and help drive impact on patients’ lives
Work with research, development, marketing, and cross-functional teams to drive commercial decision-making for early-stage, late-stage, and business development opportunities
Lead long-term vision, commercial assessment, and investment case development for early/late-stage assets, life-cycle options, and technology platforms
Lead and support portfolio-wide strategic initiatives
Interface with Global Marketing, R&D, Medical, Regulatory, Market Access, Business Development, and partner functions
Facilitate execution of asset plans and progression through governance stage-gates and enterprise governance endorsements
Foster a strong, collaborative partnership culture
Evaluate and maintain comprehensive views of competitive landscapes across assets, mechanisms of action, tumors, and oncology
Analyze global market trends, treatment trends, evolving standards of care, and competitive developments
Provide commercial input to development strategies
Drive pipeline asset and disease-area strategies, commercial assessments, product concepts, target product profiles, strategic scenario planning, and asset investment decisions
Make strategic and investment recommendations to Oncology and Pfizer governance bodies
Create and update portfolio decision-making tools and systems

Requirements

What you’ll need

Bachelor's degree with at least 8 years of experience; OR master's degree with at least 7 years of experience; OR PhD with 5+ years of experience
Experience in commercial development, marketing, new product launch or strategy in pharmaceutical, medical device or biotechnology companies
Experience in Strategy Consulting and/or Commercial organizations is preferred
Strong understanding of Oncology landscape and emerging trends
Prior Commercial Development experience with commercial planning, decision-making and driving value of early-stage pipeline assets
Experience progressing assets through development stage-gates and presenting asset business cases to senior management
Hands-on experience leading financial valuation, forecasting, business proposal and/or other related projects
Experience interfacing/collaborating with Research, Development, Regulatory, and other functions
Ability to influence without direct authority
Demonstrated leadership of cross functional matrix teams and developing a collaborative culture
Ability to coach others and oversee the work of other colleagues
High sense of urgency with a focus on driving decisions amid incomplete and imperfect information
Experience in long-term strategic plan development and execution
Experience with global product launches and developing pre-launch positioning and strategies
Candidate must be authorized to be employed in the U.S. by any employer
U.S. work visa sponsorship is not available now or in the future
Position requires permanent work authorization in the United States

Benefits

Comp & perks

Pfizer Global Performance Plan with a bonus target of 20.0% of base salary
Share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility