Head of AI Clinical Excellence

Pfizer

. Develop and execute the enterprise strategy for AI-enabled Clinical Excellence across Clinical Development .

Posted 10/12/2026full-timeUnited StatesLead💰 $176,600 - $294,300 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in AI-enabled Clinical Excellence, focusing on the development and execution of strategies that enhance clinical trial performance and operational excellence. Proficient in predictive analytics, regulatory compliance, and leading cross-functional teams in the pharmaceutical and biotechnology sectors.

Highest-signal resume keywords

AI-Enabled Clinical ExcellencePredictive AnalyticsRegulatory ComplianceClinical DevelopmentMachine Learning Solutions

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

AI DevelopmentMachine LearningAdvanced AnalyticsClinical Trial DesignData ScienceGenerative AILarge Language ModelsWorkflow AutomationClinical InformaticsOncology Expertise

Soft Skills

Excellent CommunicationExecutive InfluencingTeam LeadershipChange ManagementRelationship Building

Tools & Technologies

AI-Powered ToolsClinical Data Review PlatformsRegulatory FrameworksValidation ApproachesRisk Management Processes

Industry Keywords

PharmaceuticalBiotechnologyCRORegulatory AffairsClinical OperationsGCPFDAEMAMHRAHealth Canada

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Develop and execute the enterprise strategy for AI-enabled Clinical Excellence across Clinical Development
Identify high-value AI opportunities to accelerate development timelines, improve quality, reduce operational burden, and enhance decision-making
Advise senior leaders on emerging AI capabilities, industry trends, and competitive advancements
Drive adoption of AI across study design, protocol optimization, feasibility assessments, patient recruitment, trial execution, and clinical data review
Lead development of AI-enabled approaches to improve clinical trial performance, operational excellence, and portfolio decision-making
Enable predictive and prescriptive analytics for program-level and study-level decisions
Partner with digital, data science, and technology teams to design, build, validate, and deploy AI-powered tools and platforms
Establish scalable AI frameworks integrated into clinical development workflows
Develop agentic AI, generative AI, predictive analytics, and workflow automation solutions
Provide subject matter expertise on global regulatory expectations for AI, machine learning, and advanced analytics in drug development
Establish AI governance frameworks, validation approaches, and risk management processes with Regulatory Affairs and Quality
Monitor evolving health authority guidance and industry standards
Build partnerships across Clinical Development, Clinical Operations, Biostatistics, Regulatory Affairs, Medical, Safety, and Digital organizations
Lead multidisciplinary AI innovation teams and drive adoption through education, change management, and capability building
Represent Pfizer in industry forums, consortiums, health authority interactions, and scientific conferences
Build relationships with external partners, technology providers, and academic collaborators
Occasional travel may be required

Requirements

What you’ll need

MD and 4+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations OR PhD in Life Sciences, Clinical Research, Data Science, Biostatistics, Computer Science, Engineering, or related field and 5+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations OR MS in those fields and 7+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations
Experience designing, developing, and implementing AI, machine learning, or advanced analytics solutions in clinical research settings
Experience supporting Clinical Development, Clinical Operations, Clinical Science, Clinical Data Review, or Regulatory Science activities
Experience leading cross-functional programs involving clinical, regulatory, scientific, and technical stakeholders
Strong understanding of GCP, clinical trial conduct, drug development processes, and regulatory requirements
Experience translating complex scientific or operational challenges into scalable technology-enabled solutions
Excellent communication and executive influencing skills
Expertise in Clinical Development, Oncology, Regulatory Science, Data Science, or Clinical Informatics
Experience developing and deploying Large Language Models (LLMs), Generative AI, Agentic AI systems, or workflow automation platforms in regulated environments
Experience in Oncology
Familiarity with emerging regulatory frameworks governing AI-enabled drug development
Experience interacting with global regulatory agencies (e.g. FDA, EMA, MHRA, PMDA, Health Canada)
Experience leading enterprise AI transformation initiatives
Strong publication record and scientific credibility within clinical research and AI innovation
Experience building and leading high-performing teams
Candidates must be authorized to be employed in the U.S. by any employer
This position requires permanent work authorization in the United States
U.S. work visa sponsorship is not available for this role now or in the future

Benefits

Comp & perks

Bonus target of 20.0% of base salary through Pfizer’s Global Performance Plan
Eligibility to participate in Pfizer’s share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility