Head of AI Clinical Excellence

Pfizer

. Develop and execute the enterprise strategy for AI-enabled Clinical Excellence across Clinical Development .

Posted 10/12/2026full-timeUnited StatesLead💰 $176,600 - $294,300 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in AI-enabled Clinical Excellence, focusing on the development and execution of strategies that enhance clinical trial performance and operational excellence. Proficient in predictive analytics, regulatory compliance, and leading cross-functional teams to drive AI adoption in clinical research.

Highest-signal resume keywords

AI Strategy DevelopmentClinical Development ExpertiseRegulatory Compliance KnowledgeMachine Learning ImplementationCross-Functional Leadership

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Applicant Tracking System Keywords

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Hard Skills

AI Solutions DevelopmentPredictive AnalyticsGenerative AILarge Language Models (LLMs)Workflow AutomationClinical Trial DesignData ScienceBiostatisticsRegulatory ScienceClinical Informatics

Soft Skills

Excellent CommunicationExecutive InfluencingTeam LeadershipCollaborationChange Management

Industry Keywords

PharmaceuticalBiotechnologyCROHealthcareGCPOncologyRegulatory AffairsClinical OperationsHealth Authority GuidanceAI Governance

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Develop and execute the enterprise strategy for AI-enabled Clinical Excellence across Clinical Development
Identify opportunities to accelerate development timelines, improve quality, reduce operational burden, and enhance decision-making through AI
Advise senior leaders on emerging AI capabilities, industry trends, and competitive advancements
Drive adoption of AI solutions across study design, protocol optimization, feasibility assessments, patient recruitment, trial execution, and clinical data review
Lead AI-enabled approaches to improve clinical trial performance, operational excellence, and portfolio decision-making
Enable predictive and prescriptive analytics for program-level and study-level decisions
Partner with digital, data science, and technology teams to design, build, validate, and deploy AI-powered tools and platforms
Establish frameworks for scalable AI solutions integrated into clinical development workflows
Develop agentic AI, generative AI, predictive analytics, and workflow automation solutions supporting clinical operations and development teams
Provide subject matter expertise on global regulatory expectations for AI, machine learning, and advanced analytics within drug development
Partner with Regulatory Affairs and Quality to establish AI governance frameworks, validation approaches, and risk management processes
Monitor evolving health authority guidance and industry standards related to AI-enabled development activities
Build partnerships across Oncology Clinical Development, Clinical Operations, Biostatistics, Regulatory Affairs, Medical, Safety, and Digital organizations
Lead multidisciplinary teams responsible for AI innovation initiatives
Drive organizational adoption through education, change management, and capability building
Represent the organization in industry forums, consortiums, health authority interactions, and scientific conferences
Build relationships with external partners, technology providers, and academic collaborators
Occasional travel may be required

Requirements

What you’ll need

MD and 4+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations OR PhD in Life Sciences, Clinical Research, Data Science, Biostatistics, Computer Science, Engineering, or related field and 5+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations OR MS in Life Sciences, Clinical Research, Data Science, Biostatistics, Computer Science, Engineering, or related field and 7+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations
Experience designing, developing, and implementing AI, machine learning, or advanced analytics solutions in clinical research settings
Experience supporting Clinical Development, Clinical Operations, Clinical Science, Clinical Data Review, or Regulatory Science activities
Experience leading cross-functional programs involving clinical, regulatory, scientific, and technical stakeholders
Strong understanding of GCP, clinical trial conduct, drug development processes, and regulatory requirements
Experience translating complex scientific or operational challenges into scalable technology-enabled solutions
Excellent communication and executive influencing skills
Expertise in Clinical Development, Oncology, Regulatory Science, Data Science, or Clinical Informatics
Experience developing and deploying Large Language Models (LLMs), Generative AI, Agentic AI systems, or workflow automation platforms in regulated environments
Experience in Oncology
Familiarity with emerging regulatory frameworks governing AI-enabled drug development
Experience interacting with global regulatory agencies (e.g. FDA, EMA, MHRA, PMDA, Health Canada)
Experience leading enterprise AI transformation initiatives
Strong publication record and scientific credibility within clinical research and AI innovation
Experience building and leading high-performing teams
Breadth of diverse leadership experiences and capabilities, including influencing and collaborating with peers, developing and coaching others, and overseeing and guiding colleagues to achieve meaningful outcomes and business impact
Candidates must be authorized to be employed in the U.S. by any employer
Permanent work authorization in the United States is required
U.S. work visa sponsorship is not available now or in the future

Benefits

Comp & perks

Pfizer Global Performance Plan with a bonus target of 20.0% of the base salary
Share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility