Senior Clinical Research Associate I

Pfizer

. Manage and monitor assigned investigator sites from site initiation through database lock and close-out .

Posted 11/11/2026full-timeRemote • IsraelSeniorWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive knowledge of clinical trial methodologies, ICH/GCP, and FDA regulations while managing investigator sites and ensuring compliance with study protocols. Capable of facilitating communication among study teams and providing training to site personnel to support patient safety and trial integrity.

Highest-signal resume keywords

Clinical Trial MonitoringICH/GCP ComplianceOncology ExperienceSite ManagementPatient Safety

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial MethodologiesDatabase Lock ProceduresAdverse Event MonitoringProtocol TrainingSite Activation SupportTrial Master File DocumentationData Query ResolutionInvestigational Product HandlingCAPA DevelopmentRemote Monitoring

Soft Skills

CoachingCommunicationProblem-SolvingCollaborationTraining

Certifications & Qualifications

Bachelor’s Degree in Life SciencesValid Driver’s LicensePassport

Industry Keywords

Good Clinical PracticesFDA RegulationsOncologyVaccinesInternal MedicineInfectious DiseasesGlobal Clinical TrialsSite InitiationStudy Monitoring PlanPatient Eligibility

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Manage and monitor assigned investigator sites from site initiation through database lock and close-out
Ensure clinical trials comply with the Study Monitoring Plan, applicable laws, Good Clinical Practices and Pfizer standards
Serve as primary contact for assigned investigator sites during study conduct
Facilitate information flow among study team members, vendors and investigator sites
Coach and train site personnel and provide protocol training
Support enrollment and resolve site activation and recruitment issues
Conduct onsite and remote/electronic monitoring for site initiation, routine monitoring and closure
Monitor adverse events and serious adverse events and collaborate with the Drug Safety Unit
Submit Trial Master File documentation, site reports, follow-up letters, protocol deviations, recruitment and study progress updates
Identify and resolve site issues and develop corrective and preventative actions
Resolve data queries and conduct investigator site close-out activities
Oversee investigational product receipt, handling, accounting, storage and destruction
Support database release and undertake unblinded monitor responsibilities when required
Maintain knowledge of the product, protocol and therapy area
Support patient safety, eligibility and clinical guidance for investigators
Drive Quality Event remediation and audit observation CAPA development when applicable

Requirements

What you’ll need

Bachelor’s degree in life sciences or professional degree in life sciences such as nursing, pharmacy, medical background or equivalent
Extensive knowledge of clinical trial methodologies, ICH/GCP, FDA and local country regulations
Minimum 3 years of relevant experience in clinical research site monitoring
Preferably 2 years in Oncology
Preferred therapeutic experience in Oncology, Vaccines, Internal Medicine or Infectious Diseases
Global clinical trial experience
Fluent in English and the native language(s) of the country they will work in
Valid driver’s license and passport required
Significant travel (60–80%) within area required
May require international and weekend travel

Benefits

Comp & perks

Flexible workplace culture supporting work-life harmony
Reasonable adjustments for disability inclusion
Equal employment opportunities
Significant travel within the area and possible international travel