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Pfizer

Senior Director, Clinical Excellence Group Lead – I&I

Pfizer

. Lead and develop a team of clinical scientists .

Posted 10/23/2026full-timeUnited StatesSenior💰 $214,900 - $358,100 per yearWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates expertise in leading clinical research teams, ensuring clinical integrity, and implementing AI/ML tools for clinical trial optimization. Possesses strong capabilities in strategic planning, cross-functional collaboration, and regulatory compliance within the pharmaceutical industry.

Highest-signal resume keywords
Clinical Research LeadershipAI/ML ImplementationCross-Functional CollaborationRegulatory ComplianceClinical Trial Optimization

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills
Clinical DevelopmentPortfolio ManagementData GovernanceAdvanced AnalyticsProtocol OptimizationPatient RecruitmentSignal IdentificationSafety-Risk PredictionLifecycle ManagementBiostatistics
Soft Skills
Executive PresenceCommunication SkillsMentoringTeam DevelopmentOrganizational Change Management
Tools & Technologies
AI ToolsMachine LearningDigital ToolsClinical Trial TechnologyDashboards
Certifications & Qualifications
PhDPharmD
Industry Keywords
GxP EnvironmentsInflammation & ImmunologyClinical OperationsBusiness DevelopmentRegulatory Submissions

About the role

Key responsibilities & impact
  • Lead and develop a team of clinical scientists
  • Ensure oversight of clinical integrity, scientific quality, patient safety, and disciplined execution across Dermatology Franchise studies
  • Guide organizational change, digital transformation, and new ways of working
  • Build partnerships across Clinical Operations, Data Science, Biostatistics, Digital/Technology, Regulatory, Medical Affairs, Portfolio Strategy, and Business Operations
  • Lead portfolio planning, lifecycle management, and evaluation of future growth opportunities
  • Identify clinical-development bottlenecks and lead cross-functional workstreams to implement scalable solutions
  • Develop operating practices, tools, governance approaches, and standardized frameworks
  • Generate business insights, metrics, and dashboards for decision-making and therapeutic-area performance
  • Identify and implement AI/ML and advanced analytics tools for clinical trial design and execution
  • Apply AI/ML to protocol optimization, site selection, patient recruitment, query management, data cleaning, anomaly detection, signal identification, and safety-risk prediction
  • Incorporate AI-derived insights into clinical strategy and regulatory deliverables
  • Oversee clinical execution and integrity of high-complexity I&I dermatology studies
  • Provide senior clinical oversight for protocols, clinical documentation, CSRs, and regulatory submissions
  • Oversee study delivery, quality, and operational excellence
  • Serve as senior clinical escalation point and strategic partner to Product Team Leads, Global Development Leads, investigators, and study teams
  • Support external opportunity evaluations, business development assessments, and due diligence

Requirements

What you’ll need
  • Advanced scientific or clinical degree required; PhD, PharmD, or equivalent advanced degree strongly preferred
  • 10+ years of progressive clinical research and development experience in the pharmaceutical or biotechnology industry
  • Experience supporting global clinical programs in regulated GxP environments
  • Proven people leadership experience building, mentoring, developing, and inspiring high-performing clinical or cross-functional teams
  • Demonstrated ability to bridge clinical science with business operations and lead cross-functional workstreams
  • Exceptional executive presence and communication skills
  • Strategic or applied experience using AI, machine learning, automation, digital tools, or advanced analytics
  • Familiarity with AI-enabled clinical development use cases
  • Ability to partner with data science, digital, technology, clinical operations, bioinformatics, commercial, medical affairs, and other stakeholders
  • Strong understanding of data governance, model risk, compliance, privacy, and ethical AI considerations
  • Permanent work authorization in the United States
  • Candidates must be authorized to be employed in the U.S. by any employer; U.S. work visa sponsorship is unavailable
  • Preferred: deep subject matter expertise in Inflammation & Immunology dermatology
  • Preferred: organizational change management or digital transformation experience
  • Preferred: real-world data, digital endpoints, and decentralized or innovative clinical trial technology experience
  • Preferred: portfolio strategy, resource planning, financial modeling, or business analytics experience

Benefits

Comp & perks
  • Global Performance Plan bonus target of 22.5% of base salary
  • Share-based long-term incentive program eligibility
  • 401(k) plan with Pfizer Matching Contributions
  • Additional Pfizer Retirement Savings Contribution
  • Paid vacation
  • Paid holidays and personal days
  • Paid caregiver/parental and medical leave
  • Medical, prescription drug, dental, and vision coverage
  • Relocation assistance may be available based on business needs and/or eligibility