Senior Director, Clinical Excellence Group Lead – I&I

Pfizer

. Lead and develop a team of clinical scientists .

Posted 10/23/2026full-timeUnited StatesSenior💰 $214,900 - $358,100 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in leading clinical development programs with a focus on AI/ML integration, operational excellence, and strategic oversight in the pharmaceutical industry. Proven ability to build and mentor high-performing teams while ensuring compliance and quality in clinical research.

Highest-signal resume keywords

Clinical Research LeadershipAI/ML IntegrationRegulatory ComplianceCross-Functional Team CollaborationOperational Excellence

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical DevelopmentProtocol DesignData GovernanceResource PlanningFinancial ModelingAdvanced AnalyticsDigital TransformationPortfolio StrategyClinical Trial DesignPatient Recruitment

Soft Skills

People LeadershipCommunication SkillsExecutive PresenceMentoringStrategic Thinking

Tools & Technologies

AI ToolsMachine LearningDigital ToolsAutomationClinical Trial Technologies

Certifications & Qualifications

PhDPharmD

Industry Keywords

Pharmaceutical IndustryBiotechnologyGxP EnvironmentsDermatologyInflammation & Immunology

About the role

Key responsibilities & impact

Lead and develop a team of clinical scientists
Provide strategic clinical, scientific, operational, and people leadership across complex clinical development programs
Ensure clinical integrity, scientific quality, patient safety, and disciplined execution across Dermatology Franchise studies
Guide digital transformation and adoption of innovative tools and process optimizations
Build partnerships across Clinical Operations, Data Science, Biostatistics, Digital/Technology, Regulatory, Medical Affairs, Portfolio Strategy, and Business Operations
Lead portfolio planning, lifecycle management, and evaluation of future growth opportunities
Identify operational bottlenecks and lead cross-functional workstreams to implement scalable solutions
Develop operating practices, tools, and governance approaches with enterprise teams
Evaluate program designs, resource needs, and workflows; optimize resources and support milestones
Generate business insights, metrics, and dashboards for decision-making and therapeutic-area performance
Identify, develop, and implement AI/ML and advanced analytics tools for clinical trial design and execution
Apply AI/ML to protocol optimization, site selection, patient recruitment, query management, data cleaning, anomaly detection, signal identification, and safety risk prediction
Incorporate AI-derived insights into clinical strategy and regulatory deliverables
Oversee clinical execution and integrity of high-complexity I&I dermatology studies
Provide senior clinical oversight for protocol design, clinical documentation, and regulatory submissions
Oversee study delivery, quality, and operational excellence; serve as a senior clinical escalation point
Contribute to external opportunity evaluation, business development assessments, and due diligence

Requirements

What you’ll need

Advanced scientific or clinical degree required; PhD, PharmD, or equivalent advanced degree strongly preferred
10+ years of progressive clinical research and development experience in the pharmaceutical or biotechnology industry
Experience supporting global clinical programs in regulated GxP environments
Proven people leadership experience building, mentoring, developing, and inspiring high-performing clinical or cross-functional teams
Demonstrated ability to bridge clinical science with business operations and lead cross-functional workstreams
Exceptional executive presence and communication skills
Strategic or applied experience using AI, machine learning, automation, digital tools, or advanced analytics
Familiarity with AI-enabled clinical development use cases
Ability to partner with data science, digital, technology, clinical operations, bioinformatics, commercial, medical affairs, and other stakeholders
Understanding of data governance, model risk, compliance, privacy, and ethical AI considerations in pharmaceutical development
Pfizer requires permanent work authorization in the United States; U.S. work visa sponsorship is not available
Preferred: Inflammation & Immunology dermatology expertise; organizational change management or digital transformation; real-world data; digital endpoints; decentralized or innovative clinical trial technologies; portfolio strategy; resource planning; financial modeling; business analytics

Benefits

Comp & perks

Global Performance Plan bonus target of 22.5% of base salary
Share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility