Senior Director, PMO, COE

Pfizer

. Shape and support External Supply strategy, intelligence, governance, and execution .

Posted 9/16/2026full-timeCollegeville • Pennsylvania • United StatesSenior💰 $214,900 - $358,100 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Strategic Leadership, Program Management, and Operational Excellence within the pharmaceutical manufacturing and supply chain sectors. Proven ability to drive Digital Transformation, AI Adoption, and Continuous Improvement while managing complex, cross-functional initiatives and executive stakeholder alignment.

Highest-signal resume keywords

Strategic LeadershipProgram ManagementOperational ExcellencePharmaceutical ManufacturingDigital Transformation

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Program ManagementGovernance FrameworksCapacity PlanningData AnalyticsAI AdoptionLean Six SigmaOperational ExcellenceChange ManagementBusiness Process DesignPortfolio Management

Soft Skills

Excellent CommunicationInfluencing SkillsAnalytical SkillsTeam LeadershipStakeholder Alignment

Tools & Technologies

DashboardsAutomation ToolsEmerging AI CapabilitiesCRM ProcessesBusiness Review Metrics

Certifications & Qualifications

Lean Six Sigma Black BeltAI CertificationPMP CertificationAgile Certification

Industry Keywords

Supply Chain OperationsExternal ManufacturingNetwork StrategyPharmaceutical Business DevelopmentOperational Feasibility

Tech Stack

Tools & technologies

PMP

About the role

Key responsibilities & impact

Shape and support External Supply strategy, intelligence, governance, and execution
Provide strategic leadership for ES Vision and Strategy, EMAP Operating Efficiencies, Program Management, and Center of Excellence capabilities
Provide executive oversight of the ES strategic portfolio and PC1 technology transfer program portfolio
Establish governance and prioritization frameworks for resource allocation, sequencing, dependencies, risks, and strategic tradeoffs
Lead ES Vision and Strategy deployment and value realization
Lead the EMAP Operating Efficiencies Polaris multi-year savings program targeting a 6% reduction in total ES vendor spend
Oversee the ES Program Management Office and strategic initiative execution
Establish program management standards, governance processes, methodologies, and reporting expectations
Manage program risks, dependencies, issues, escalations, and value realization
Oversee governance and execution of the PC1 technology transfer portfolio
Coordinate with Pfizer Site leaders, Client Senior Leaders including CEO-level executives, and PGS/ES senior leadership
Lead, coach, and develop the CoE team of 10 direct reports across Ireland and Tampa hubs
Build capability in Continuous Improvement, Digital Transformation, AI adoption, and Process Excellence
Manage resource allocation and workforce planning across ES Categories and Clusters
Design and implement new business processes
Direct Category governance, IMEx forums, VSLT operating reviews, and CRM/BRM processes
Direct development of dashboards, metrics, and business reviews
Serve as senior Operational Excellence authority and lead capability-building programs
Direct operational support including VSOT governance, category issue resolution, supplier/sample-shipment coordination, and T4 Continuous Improvement Loop activities
Champion AI fluency, digital transformation, change management, audit readiness, and compliance governance
Transition projects into BAU, establish process ownership and governance, embed best practices, integrate processes into Category operations, and monitor benefits realization
Perform other responsibilities as assigned

Requirements

What you’ll need

Bachelor's degree with at least 12 years of experience; OR master's degree with at least 10 years of experience; OR PhD with 7+ years of experience
Progressive leadership experience in strategy, program management, supply chain, network strategy, operational excellence, pharmaceutical manufacturing, business development, or related disciplines
Demonstrated experience leading complex, cross-functional initiatives and influencing executive-level decision-making within a matrixed global organization
Experience translating strategic priorities into executable plans and delivering measurable business outcomes through governance and stakeholder alignment
Experience supporting executive leadership through strategic assessments, business case development, portfolio evaluations, or enterprise decision-making processes
Experience leading and developing high-performing teams across functions and geographies
Strong understanding of pharmaceutical manufacturing, supply chain operations, external manufacturing networks, capacity planning, and network strategy principles
Strong business acumen evaluating tradeoffs across cost, capacity, risk, growth, operational feasibility, and strategic priorities
Exceptional analytical and synthesis skills
Excellent communication and influencing skills
Ability to establish governance frameworks, drive accountability, and create organizational clarity
Ability to operate effectively in fast-paced, evolving environments
Strong digital fluency, including analytics, dashboards, automation, and emerging AI-enabled capabilities
Fluency in English
Lean Six Sigma Black Belt OE Certification preferred
AI Certification preferred
Experience in network strategy, supply chain strategy, external manufacturing, CMOs/CDMOs, or pharmaceutical business development preferred
Experience with major network decisions, including sourcing strategy, acquisitions, divestitures, make-versus-buy assessments, portfolio rationalization, capacity planning, or strategic investments preferred
Experience establishing governance models, strategic planning frameworks, or enterprise decision-support capabilities preferred
Experience working with Digital, Data, Analytics, or Technology organizations preferred
Experience leading large strategic portfolios, enterprise transformation initiatives, or PMO organizations preferred
Experience supporting technology transfer programs, manufacturing transfers, product launches, or network optimization initiatives preferred
Lean Six Sigma, Operational Excellence, PMP, Agile, or equivalent certification preferred
Knowledge of emerging digital, data, analytics, automation, and AI capabilities preferred
Candidates must be authorized to be employed in the U.S. by any employer
U.S. work visa sponsorship is not available now or in the future
Permanent work authorization in the United States is required

Benefits

Comp & perks

Pfizer Global Performance Plan bonus target of 22.5% of base salary
Share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility