Clinical Trial Manager

Sigma Systems

. Lead the U.S. local clinical trial team and oversee day-to-day clinical trial operations . Manage trial preparation, execution, monitoring coordination, and closeout activities . Ensure clinical trials meet recruitment

Posted 11/10/2026contractRemote • Connecticut • United StatesJuniorMid-LevelWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive experience in managing clinical trials, ensuring compliance with GCP guidelines and regulatory requirements, while effectively leading cross-functional teams and maintaining trial integrity. Proven ability to oversee trial operations, manage stakeholder relationships, and implement process improvements in a fast-paced environment.

Highest-signal resume keywords

Clinical Trial ManagementGood Clinical Practice (GCP)Stakeholder ManagementCross-Functional CollaborationRisk Assessment

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Research ExperienceClinical Trial OperationsProject ManagementRegulatory CompliancePediatric Clinical TrialsTrial PreparationMonitoring CoordinationData AccuracyBudget ManagementProcess Improvement

Soft Skills

Communication SkillsOrganizational SkillsProblem-Solving SkillsConflict ResolutionInfluencing Skills

Industry Keywords

Pharmaceutical IndustryClinical Development ProcessesClinical Research Compliance StandardsTrial Closeout ActivitiesPatient Safety

About the role

Key responsibilities & impact

Lead the U.S. local clinical trial team and oversee day-to-day clinical trial operations
Manage trial preparation, execution, monitoring coordination, and closeout activities
Ensure clinical trials meet recruitment targets, project timelines, budget expectations, and quality standards
Maintain compliance with GCP guidelines, clinical research regulations, and internal quality requirements
Coordinate with Clinical Research Associates (CRAs), investigators, site staff, and Site Monitoring Leads
Serve as the primary point of contact for CRAs, investigators, and clinical research sites
Collaborate with global, regional, and cross-functional teams to ensure successful trial execution
Monitor trial progress, identify potential risks, and implement appropriate mitigation strategies
Ensure patient safety, clinical trial integrity, and accuracy of trial data
Represent the organization during internal and external meetings, including interactions with investigational sites and regulatory agencies
Manage multiple clinical trial assignments while balancing competing priorities
Contribute to process improvements and innovative clinical trial management initiatives

Requirements

What you’ll need

Bachelor's degree with a minimum of 6 years of clinical research experience; OR Master's degree or PharmD with a minimum of 4 years of clinical research experience; OR PhD or MD with a minimum of 2 years of clinical research experience
Experience managing pediatric clinical trials is required
Pharmaceutical industry experience preferred
Strong understanding of clinical trial operations, clinical development processes, and regulatory requirements
Knowledge of Good Clinical Practice (GCP) and clinical research compliance standards
Demonstrated experience in clinical trial project management and team leadership
Strong stakeholder management and cross-functional collaboration skills
Ability to manage complex clinical studies involving multiple sites, countries, suppliers, and clinical trial participants
Excellent communication, organizational, and problem-solving skills
Ability to manage competing priorities, resolve conflicts, and influence stakeholders
Strong risk assessment, planning, and coordination capabilities
Must be willing and able to travel domestically approximately 10–20% of the time
Position is primarily remote within the United States

Benefits

Comp & perks

Paid weekly
Client holidays are paid
Sick time provided in accordance with applicable local statutes