Proposal Specialist, Large Molecules – mRNA

Thermo Fisher Scientific

. Evaluate RFIs/RFPs and client inputs to confirm technical needs, identify information gaps, and recommend proposal strategy and project approach .

Posted 10/19/2026full-timeRemote • United StatesMid-LevelSenior💰 $75,800 - $113,600 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in mRNA and lipid nanoparticle (LNP) manufacturing processes, with a strong ability to translate technical requirements into comprehensive proposals, budgets, and project timelines. Excels in client-facing communication, collaboration across global teams, and operational excellence initiatives.

Highest-signal resume keywords

MRNA Manufacturing ProcessesLipid Nanoparticle (LNP) DevelopmentTechnical Proposal PreparationClient-Facing CommunicationMS Excel Proficiency

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Technical Proposal PreparationResource EstimationBudgetingProject Timeline DevelopmentAnalytical SupportScope DefinitionChange ManagementContractual Terms UnderstandingSterile Drug Product ManufacturingGood Manufacturing Practices (GMP)

Soft Skills

Attention to DetailAnalytical SkillsCollaboration SkillsOrganizational SkillsTime Management

Tools & Technologies

MS ExcelMS WordMS PowerPointMS Project

Industry Keywords

Contract Manufacturing Organization (CMO)Contract Development and Manufacturing Organization (CDMO)Operational ExcellenceProposal StrategyClient Liaison

About the role

Key responsibilities & impact

Evaluate RFIs/RFPs and client inputs to confirm technical needs, identify information gaps, and recommend proposal strategy and project approach
Generate proposals for mRNA drug substance and LNP development/manufacturing programs, including budgetary estimates, detailed scopes, Statements of Work, and Change of Scope documents
Translate technical requirements into resource/FTE estimates, pricing assumptions, project timelines, deliverables, dependencies, and proposal assumptions
Collaborate with subject matter experts across global sites to develop technically feasible scopes
Partner with Technical Subject Matter Experts, Business Development, Business Management, and Senior Leadership on program pricing and commercial positioning
Act as liaison between clients and technical teams during client calls, proposal reviews, and scope discussions
Present proposals and explain Thermo Fisher Scientific’s mRNA/LNP capabilities, technical approach, service standards, and options
Read and understand contractual terms and revise proposals to support progression through contract signature
Review and revise proposal templates, costing models, standard estimates, and timeline templates
Coordinate awarded-project handoff to Program Management and technical teams
Collaborate with proposal teams and other Business Units on integrated offering proposal strategy
Champion proposal process improvements, Operational Excellence initiatives, and internal training

Requirements

What you’ll need

Minimum of 5 years of related experience with a Bachelor's degree in a relevant scientific or technical field; or 3 years of related experience with an advanced degree
High-level technical understanding of mRNA and lipid nanoparticle (LNP) manufacturing processes and associated development and analytical support
Experience preparing technical proposals, scopes, work statements, or comparable client-facing technical documentation
Experience translating complex technical requirements into resource estimates, budgets/pricing, and project timelines
Strong client-facing communication and presentation skills
Excellent written and oral English communication skills
Strong analytical and questioning skills, attention to detail, and ability to identify scope gaps, assumptions, dependencies, and risks
Strong collaboration skills across global, matrixed teams
Proficiency in MS Excel, MS Word, MS PowerPoint, and MS Project
Experience in a CMO/CDMO environment and familiarity with Good Manufacturing Practices (GMP) is preferred
Prior mRNA and/or LNP technical experience is strongly preferred
Experience with sterile drug product manufacturing is a plus
Excellent organizational and time-management skills
Ability to balance technical requirements, operational limitations, commercial objectives, and client expectations
Ability to participate in and lead meetings across global time zones, including occasionally outside standard business hours
Ability to support customer visits, trade shows, or technical conferences as business needs require
Limited travel (5-10%) may be required

Benefits

Comp & perks

Variable annual bonus based on company, team, and/or individual performance results
National medical and dental plans
National vision plan, including health incentive programs
Employee assistance and family support programs
Commuter benefits
Tuition reimbursement
At least 120 hours paid time off (PTO)
10 paid holidays annually
Paid parental leave: 3 weeks for bonding and 8 weeks for caregiver leave
Accident and life insurance
Short- and long-term disability
Competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP), offering eligible colleagues the opportunity to purchase company stock at a discount