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WCG

Senior Principal Statistical Programmer

WCG

. Serve as a senior technical expert in statistical programming across multiple studies or functional areas .

Posted 11/3/2026full-timeRemote • United StatesSenior💰 $131,100 - $160,000 per yearWebsite

Core Competencies

Role fit
Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive expertise in SAS and R programming for statistical analysis in clinical trials, ensuring compliance with CDISC standards and regulatory requirements. Proven leadership in mentoring teams and driving programming standards and process improvements across multiple studies.

Highest-signal resume keywords
SAS ProgrammingR ProgrammingCDISC StandardsStatistical Programming LeadershipRegulatory Submissions Oversight

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills
Statistical ProgrammingComplex AnalysesProgramming Standards DevelopmentData ManagementAnalysis Datasets CreationTables Listings Figures GenerationProcess ImprovementsAutomation TechniquesTechnical OversightBiostatistical Project Coordination
Soft Skills
MentoringCollaborationTechnical LeadershipProblem SolvingCommunication
Tools & Technologies
SAS EnvironmentsStatistical SoftwareProgramming ToolsSystem Validation Tools
Industry Keywords
Clinical TrialsRegulatory RequirementsDMC ReportingStudy ProtocolsSAP Interpretation

About the role

Key responsibilities & impact
  • Serve as a senior technical expert in statistical programming across multiple studies or functional areas
  • Design, develop, validate, and oversee complex statistical programming deliverables, including analysis datasets, tables, listings, and figures
  • Lead development, validation, and continuous improvement of DMC macros and programming standards
  • Provide technical oversight and review of programming work
  • Establish and drive adoption of programming standards, best practices, and process improvements
  • Collaborate with biostatistics and study teams on complex trial designs, analyses, and DMC reporting
  • Manage and prioritize programming activities across multiple studies or initiatives
  • Mentor statistical programming staff and provide technical leadership
  • Contribute technical expertise to proposals, project planning, and scope discussions
  • Partner with IT and technology teams on SAS environments, tools, and system validation
  • Provide technical oversight for regulatory submissions and inspection readiness
  • Ensure deliverables align with regulatory expectations, submission requirements, and CDISC standards
  • Serve as a technical escalation point and lead resolution of complex programming, data, or deliverable issues
  • Interpret SAPs, protocols, and study documents and translate requirements into programming strategy
  • Champion process improvements, automation, and innovative approaches to improve efficiency and consistency
  • Perform other duties as assigned by supervisor

Requirements

What you’ll need
  • Master’s degree required; in limited circumstances, an equivalent combination of education and directly relevant professional experience may be considered
  • Minimum 8–10 years of statistical programming experience in a clinical trial environment
  • Deep expertise in SAS programming, including complex analyses and regulatory deliverables
  • Proficiency in R programming is a must
  • Demonstrated experience with CDISC standards and regulatory requirements
  • Proven ability to independently lead complex programming efforts across studies
  • Experience mentoring staff and driving technical standards or best practices
  • Demonstrated ability to independently coordinate biostatistical projects, including planning and oversight of programming activities, with minimal direction from senior leadership
  • Ability to perform each essential duty and responsibility satisfactorily

Benefits

Comp & perks
  • Medical, dental, vision, life and disability insurance
  • 401(k) with company match
  • Flexible spending accounts
  • Employee assistance programs
  • Work/life balance tools
  • Referral bonuses
  • Tuition reimbursement
  • On-the-job training
  • Certification assistance
  • Continuing education support
  • Paid holidays, vacation, and sick time
  • Career development opportunities across One WCG