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Zoetis

Scientist, Downstream Bioprocess Development

Zoetis

. Develop and optimize robust, economical downstream processes for biologics antigen production and recombinant protein purification .

Posted 9/21/2026full-timeUnited StatesMid-LevelSeniorWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates expertise in downstream processing (DSP) for biologics, including chromatography and filtration techniques, while effectively collaborating with interdisciplinary teams to optimize processes and ensure compliance with regulatory standards.

Highest-signal resume keywords
Downstream Processing (DSP)Chromatography TechniquesFiltration TechniquesAutomated Chromatography SystemsProcess Characterization and Optimization

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
ChromatographyFiltrationProcess OptimizationHPLC/LCUV-Vis SpectroscopyGel ElectrophoresisProtein AssaysAseptic TechniqueDesign of ExperimentsProtein Chemistry
Soft Skills
Strong Communication SkillsInterpersonal SkillsCollaboration
Tools & Technologies
UNICORNÄKTA ExplorerÄKTA PureÄKTA Pilot
Industry Keywords
BiologicsVaccine DevelopmentGMPRegulatory FilingsBiotechnology

About the role

Key responsibilities & impact
  • Develop and optimize robust, economical downstream processes for biologics antigen production and recombinant protein purification
  • Execute and troubleshoot chromatography and filtration unit operations, including cross-flow and dead-end filtration
  • Purify and concentrate vaccine antigens and therapeutic proteins
  • Perform process characterization and optimization studies, including Design of Experiments, to establish operational ranges and define design spaces
  • Support purification of antigens and concentration of viral and bacterial materials for mono- and multivalent vaccine development
  • Partner with pilot and manufacturing teams to scale processes and transfer them to commercial/GMP environments
  • Author protocols, study reports, and technology transfer documents for internal/external tech transfer and regulatory filings
  • Represent DSP/Process Development on interdisciplinary project teams and provide technical recommendations
  • Maintain electronic laboratory notebooks, templates, and documentation in accordance with protocols and SOPs
  • Collaborate with research, bacteriology, virology, formulation, regulatory, bioanalytical, pilot operations, manufacturing, global colleagues, and external partners

Requirements

What you’ll need
  • BSc/MSc in Microbiology, Cell Biology, Biotechnology, Chemical Engineering, Biochemical Engineering, or related discipline
  • BSc: 5–7 years relevant academic and/or industry experience in downstream processing (DSP), or MSc: 3–5 years relevant academic and/or industry experience in DSP
  • Experience developing low-pressure chromatography steps (multiple modalities) and filtration steps (cross-flow and dead-end)
  • Hands-on experience with automated chromatography systems/software, such as UNICORN and ÄKTA Explorer/Pure/Pilot
  • Experience with core analytical methods used to evaluate DSP performance, including HPLC/LC, UV-Vis, gel electrophoresis, and total protein/protein assays
  • Strong scientific fundamentals supporting DSP, including protein chemistry, biotechnology, and biochemistry
  • Experience in aseptic technique
  • Strong oral and written communication and interpersonal skills
  • Ability to work effectively with diverse personalities
  • All applicants must possess or obtain authorization to work in the US for Zoetis
  • Candidates requiring sponsorship must disclose this fact

Benefits

Comp & perks
  • Equal opportunity employment
  • Reasonable accommodations for individuals with disabilities