Research Scientist

• Support data collection and management, data project timelines, technical infrastructure, and other data tasks for research cohort studies
• Assist in developing and coordinating data collection tools, including surveys and data collection forms
• Maintain project databases such as REDCap and Ripple or similar systems
• Support database creation, data problem identification and resolution, and results reporting
• Participate in data review, cleaning, and organization
• Develop programs supporting database creation, data problem identification and resolution, and results reporting
• Collaborate with internal staff and external study partners
• Attend and actively participate in staff, data/operations, and co-investigator meetings
• Provide support to internal and external data and project collaborators
• Perform day-to-day general tasks in support of research studies
• Contribute to maintenance of software applications and relevant data and technical documentation
• Perform other duties and projects as assigned

Senior Research Assistant

• Lead qualification and onboarding of new CRO partners for ADME and bioanalytical assays
• Serve as primary scientific point of contact from technical assessment through integration
• Provide scientific oversight and strategic guidance for regulated and non-regulated bioanalytical method development, validation, and sample analysis
• Collaborate with Discovery, Non-Clinical, and Clinical teams to align CRO capabilities with program needs
• Partner with Procurement, Quality, and Operations to establish and improve CRO qualification standards and processes
• Build strategic relationships with internal customers and external vendors
• Provide bioanalytical method support, troubleshooting, and critical reagent management
• Mentor scientists and share technical expertise across the bioanalytical outsourcing network
• Travel approximately 25%

Principal Scientist – CRO Lab Qualification & Onboarding, Bioanalytical Outsourcing

• Provide scientific and research expertise across multiple concurrent observational and real-world oncology research projects
• Lead development and refinement of scientific protocols, including statistical analysis sections
• Define study data requirements using real-world data sources and feasibility assessments
• Serve as scientific point of contact for project sponsors and cross-functional teams
• Attend client meetings and support discussions of research methods, results, and interpretation
• Evaluate complex research questions from internal and external stakeholders
• Collaborate with abstraction and biostatistics teams on data collection, eCRFs, and data specifications
• Prepare client-ready deliverables, including final reports, presentations, and summaries of analytic findings
• Review and interpret statistical analysis results to assess data quality and support evidence-based conclusions
• Complete regulatory and compliance documents
• Support amendments and proposals for new research opportunities

Senior Observational Research Scientist – Oncology

• Provide scientific and research expertise across multiple concurrent real-world oncology research projects
• Lead development and refinement of scientific protocols, including statistical analysis sections
• Serve as scientific point of contact for project sponsors and cross-functional teams
• Attend client meetings and support discussions of research methods, results, and interpretation
• Evaluate complex research questions from internal and external stakeholders
• Apply real-world data expertise to define study data requirements and support data collection
• Collaborate with abstraction and biostatistics teams on eCRFs and data specifications
• Prepare client-ready deliverables, including final reports, presentations, and summaries of analytic findings
• Review and interpret statistical analysis results to assess data quality and develop evidence-based conclusions
• Complete regulatory and compliance documents
• Support amendments and proposals for new research opportunities

• Manage and contribute to coordination of multiple projects evaluating integrative therapies
• Finalize study protocols with the Project Manager
• Oversee communications with IRBs
• Recruit patients and administer phone screens
• Administer informed consent and enroll patients
• Perform data collection, interpretation, and manuscript preparation
• Manage the experience of study subjects
• Manage, manipulate, analyze, and report data
• Manage study cohorts
• Conduct outreach communications, mailings, follow-up, and document collection
• Assist with progress reports using basic prescriptive statistics
• Gather information for future research proposals
• Train and orient new staff

Research Assistant II

• Work across agroecosystems, with projects focused on regenerative agricultural practices, cover crop adoption, and grazing management systems
• Investigate and promote the role soils can play in nature-based climate solutions
• Collect soil samples in various field settings
• Process, inventory, and catalog new soil samples
• Prepare soil samples by drying, grinding, or extraction
• Follow lab safety procedures and maintain a safe, tidy work environment
• Perform routine soil laboratory testing, including pH, calcium carbonate equivalents, diffuse reflectance spectroscopy, elemental carbon and nitrogen analysis, particle-size texture analysis, colorimetric nutrient assays, microbial respiration, and enzymatic activity
• Collate data and prepare reports
• Work as part of a multidisciplinary team of PIs, research scientists, postdocs, and research assistants under supervision

Research Assistant I

• Develop, validate, and apply next-generation spatial omics and massively parallel functional genomics platforms for therapeutic discovery
• Build and deploy integrated platforms connecting genetic perturbation, genetic element function, cellular phenotypes, and tissue context
• Lead experimental workflows spanning perturbation library development, reporter assay engineering, cellular model generation, spatial molecular profiling, and multiomic data generation
• Identify regulatory mechanisms, target-effector relationships, disease-associated cellular programs, and therapeutic opportunities
• Establish and scale laboratory capabilities as an individual contributor
• Evaluate emerging technologies and manage external collaborators and CROs
• Serve as a scientific partner supporting multiple discovery programs
• Lead development, optimization, and deployment of MPRAs combined with single-cell and spatial omics
• Design workflows integrating genetic perturbation, reporter assays, molecular profiling, and spatial analysis
• Serve as a subject matter expert in spatial biology, functional genomics, and high-content genomics screening
• Design and execute in situ hybridization, microscopy, spatial transcriptomics, spatial proteomics, high-resolution imaging, and sequencing workflows
• Develop and optimize spatial assays using Bruker CosMx, 10x Genomics Visium, Xenium, and emerging technologies
• Apply spatial approaches to characterize cellular interactions, tissue architecture, disease mechanisms, and therapeutic responses
• Develop and deploy MPRAs to investigate protein elements, disease-associated variants, transcriptional control mechanisms, and cell-state-specific regulatory programs
• Design and execute pooled functional genomics studies, including CRISPR-based perturbation screens, barcode-enabled assays, and genetic screening workflows
• Lead experimental design for library construction, vector engineering, cellular model generation, assay validation, and screening campaigns
• Build workflows connecting functional perturbation data with spatial phenotypes and tissue-level biology
• Partner with computational scientists on data standards, quality-control frameworks, and scalable analytical pipelines
• Collaborate with platform and therapeutic-area scientists to translate multiomic findings into biological insights and therapeutic hypotheses

Principal Scientist, Multiomics

• Develop, validate, and apply next-generation spatial omics and massively parallel functional genomics platforms for therapeutic discovery
• Build and deploy integrated platforms connecting genetic perturbation, genetic element function, cellular phenotypes, and tissue context
• Lead experimental workflows spanning perturbation library development, reporter assay engineering, cellular model generation, spatial molecular profiling, and multiomic data generation
• Identify regulatory mechanisms, target-effector relationships, disease-associated cellular programs, and therapeutic opportunities
• Establish and scale laboratory capabilities as an individual contributor
• Evaluate emerging technologies and manage external collaborators and CROs
• Serve as a scientific partner supporting multiple discovery programs
• Lead development, optimization, and deployment of MPRAs with single-cell and spatial omics
• Design workflows integrating genetic perturbation, reporter assays, molecular profiling, and spatial analysis
• Evaluate and scale technologies for therapeutic pathway discovery, mechanism-of-action studies, and translational research
• Serve as subject matter expert in spatial biology, functional genomics, and high-content genomics screening
• Design and execute in situ hybridization, microscopy, spatial transcriptomics, spatial proteomics, high-resolution imaging, and sequencing workflows
• Develop and optimize assays using Bruker CosMx, 10x Genomics Visium, Xenium, and emerging technologies
• Apply spatial approaches to characterize cellular interactions, tissue architecture, disease mechanisms, and therapeutic responses
• Develop and deploy MPRAs investigating protein elements, disease-associated variants, transcriptional control mechanisms, and cell-state-specific regulatory programs
• Design and execute pooled functional genomics studies, including CRISPR perturbation screens, barcode-enabled assays, and genetic screening workflows
• Lead experimental design for library construction, vector engineering, cellular model generation, assay validation, and screening campaigns
• Build workflows connecting functional perturbation data with spatial phenotypes and tissue-level biology
• Partner with computational scientists on data standards, quality-control frameworks, and scalable analytical pipelines
• Collaborate with platform and therapeutic area scientists to translate multiomic findings into biological insights and therapeutic hypotheses

• Serve as the primary subject matter expert and technical point of contact for the CG BIO partnership
• Lead technical activities and decisions between external R&D teams and internal DePuy Synthes teams
• Support initial global launches and product lifecycle management
• Optimize and improve Novosis formulations and procedural kits
• Ensure handling characteristics, release kinetics, and bioactivity meet global spine and trauma market needs
• Translate orthopedic and neurosurgeon user needs into actionable technical specifications
• Lead brainstorming and technical collaborations to develop priority concepts
• Develop pre-clinical, clinical, regulatory, and reimbursement strategies
• Act as the primary subject matter expert on rhBMP-2 and advanced bone graft substitutes
• Develop technical training modules and educational materials for global sales and marketing teams
• Engage KOLs, spine surgeons, and trauma specialists through technical education and surgical training labs
• Gather customer feedback and present at global technical conferences
• Partner with Medical Affairs, HEMA, and Clinical teams on evidence generation strategies
• Analyze biochemical and biomechanical data for marketing collateral
• Author white papers, scientific publications, and technical reports

Principal Scientist, R&D – Orthopedics, Growth Factors

• Serve as primary subject matter expert and technical point of contact for the CG BIO partnership
• Lead technical activities and decisions between external R&D teams and internal DePuy Synthes teams for global launches and product lifecycle management
• Partner with CG BIO to optimize Novosis formulations and procedural kits
• Ensure handling characteristics, release kinetics, and bioactivity meet global spine and trauma market needs
• Translate orthopedic and neurosurgeon user needs into technical specifications
• Lead brainstorming and technical collaborations for priority concepts
• Develop robust development, pre-clinical, clinical, regulatory, and reimbursement strategies
• Act as subject matter expert on rhBMP-2 and advanced bone graft substitutes
• Develop technical training modules and educational materials for global sales and marketing teams
• Engage KOLs, spine surgeons, and trauma specialists through technical education and surgical training labs
• Gather customer feedback and present at global technical conferences
• Partner with Medical Affairs, HEMA, and Clinical teams on evidence generation strategies
• Analyze biochemical and biomechanical data for marketing collateral
• Author white papers, scientific publications, and technical reports

Research Scientist jobs in Massachusetts

Senior Research Assistant

Principal Scientist – CRO Lab Qualification & Onboarding, Bioanalytical Outsourcing

Senior Observational Research Scientist – Oncology

Senior Observational Research Scientist – Oncology

Research Assistant II

Research Assistant I

Principal Scientist, Multiomics

Principal Scientist, Multiomics

Principal Scientist, R&D – Orthopedics, Growth Factors

Principal Scientist, R&D – Orthopedics, Spine, Growth Factors