ICON plc

Physician

• Provide senior medical and radiology leadership for sponsor studies, including imaging strategy, protocol design, imaging manuals, read methodology, charters, system requirements, training materials, quality control and independent reviewer processes
• Partner with Business Development and operational teams on new business opportunities, bid defenses, capabilities meetings and client relationship development
• Represent ICON’s medical, scientific and imaging expertise in internal and external discussions
• Support responses to requests for proposals and information with scientific, medical and technical input
• Provide real-time consultation on imaging-related scientific and operational questions, including protocol development, radiology case review, contrast use, imaging analysis, read design, read criteria and issue resolution
• Build trusted client relationships by advising on imaging strategy and supporting regulatory authority responses
• Supervise independent read teams, including reader training, Q&A, performance monitoring, inter-reader variability assessment, retraining plans and read-quality oversight
• Oversee imaging reads and provide medical review and guidance
• Participate in industry forums, imaging standardization initiatives, scientific meetings and external presentations
• Mentor medical, scientific and operational colleagues
• Lead, motivate and advise project and study teams
• Guide medical and scientific activities for timely, complete and client-focused delivery
• Develop capability across medical, scientific and operations teams by translating complex concepts into practical study guidance

Senior Supervising Radiologist

Clinical Operations

• Manage day-to-day clinical trial management activities
• Plan and manage all aspects of clinical trials, ensuring adherence to timelines, budget, and quality standards
• Collaborate with cross-functional teams to establish and implement clinical trial protocols and procedures
• Build and manage strong relationships with trial investigators and stakeholders
• Ensure trials comply with local, national, and international regulations and ethical guidelines
• Problem-solve and make critical decisions regarding trial design, vendor selection, and risk management
• Support the team and stakeholders to deliver high-quality outcomes across clinical programmes
• Develop the team and manage competing priorities

Manager, Clinical Operations

Human Resources

• Serve as a strategic partner to business leaders, providing HR expertise aligned with organizational goals
• Oversee human resources delivery, coach the team, and drive continuous improvement
• Partner with senior leadership to develop and implement HR strategies supporting business objectives and organizational effectiveness
• Advise on talent acquisition, performance management, and succession planning
• Drive employee engagement initiatives and promote inclusivity and collaboration
• Analyze workforce metrics and trends to identify improvement opportunities and inform strategic decisions
• Lead and mentor a team of HR professionals, fostering continuous development and accountability

Senior Manager, HR Business Partner

Clinical Trial Associate

• Assist in the coordination and administration of clinical trials, ensuring compliance with protocols and regulatory requirements
• Maintain and organize clinical trial documentation, including study files, essential documents, and regulatory submissions
• Support the preparation of study-related materials, such as informed consent forms and case report forms
• Work with cross-functional teams to facilitate communication and ensure smooth trial execution
• Contribute to the tracking and reporting of clinical trial metrics and milestones
• Assist with the design and analysis of clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies

Clinical Research

• Oversee and manage clinical trial activities according to protocol, regulatory requirements, and industry standards
• Lead clinical trial monitoring tasks requiring technical depth, focusing on quality and continuous improvement
• Monitor clinical trial sites for adherence to study protocols, regulatory requirements, and GCP standards
• Conduct site visits to assess performance, resolve issues, and support successful trial execution
• Collaborate with cross-functional teams to ensure timely and accurate data collection and reporting
• Provide training and guidance to site staff and other CRAs
• Build and maintain relationships with site personnel and stakeholders
• Monitor cardiovascular and respiratory studies

Senior Clinical Research Associate

Analyst

• Prepare, verify, and carry out invoicing via electronic processing and reporting activities for an assigned portfolio of accounts
• Contribute to contract management activities and take responsibility for deliverables
• Negotiate directly with assigned sites on clinical trial agreements, budgets, payment terms, ancillary agreements, and amendments
• Partner with internal Study Startup team, CROs, Clinical Operations teams, and TAU partners to improve SB&C metrics and deliver processes
• Ensure standards are applied to SB&C processes across projects
• Use industry tools and data sources to provide budget and contract feedback aligned with parameters and fair market value guidance
• Recognize and improve potential delays and escalate to appropriate team members
• Track actions and negotiations to achieve study and site timelines
• Support resolution of escalated issues identified by the site activation sub-team with the internal Study Startup team

Contract Analyst I

• Coordinate clinical trial management delivery
• Resolve clinical trial issues
• Develop team capability
• Oversee the clinical portion of the budget to ensure efficient resource allocation
• Develop monitoring plans and tools, ensuring effective study oversight
• Train and mentor Clinical Research Associates (CRAs)
• Drive enrollment and lead study start-up activities while adhering to timelines
• Review trip reports and implement corrective and preventative action plans when necessary
• Foster productive relationships with Sponsors, vendors, and cross-functional teams

Senior Clinical Trial Manager

• Manage the grant application process from start to finish
• Research and identify grant opportunities aligned with the organization's mission and values
• Collaborate with internal stakeholders to gather information and develop grant proposals
• Ensure compliance with grant funding requirements and deadlines
• Track and report on grant activities and outcomes
• Contribute to scientific operations activities and take responsibility for deliverables

Payment Analyst

Pharmacist

• Inspect and dispense experimental drugs for clinical trial patients
• Review and edit clinical protocols, batch records/preparation records, and IMPDs by generating, collecting, and analyzing trial data
• Oversee manufacturing aspects of Chemistry, Manufacturing and Control (CMC) projects in GMP environments
• Serve as a resource for investigational drug-related inquiries
• Maintain drug accountability by compiling and documenting accurate patient dosages
• Advise medical staff on investigational medicinal products, including use, type, and route of administration
• Plan and evaluate IMP programs and regimens, ensuring processes, data, and samples are properly recorded and stored
• Draft manufacturing and compounding batch records
• Manage facility parameters to ensure CMC project compliance with GMP
• Read and review IMPDs or Investigational New Drugs (INDs)

Research Pharmacist

• Coordinate and develop contracts and change orders for newly awarded and ongoing projects
• Work simultaneously on numerous contracts and/or change orders and develop more complicated budgets
• Lead discussions with ICON Legal, Sales, and Contracts Managers to determine appropriate contract terms and conditions
• Use ICON costing tools, client budget grids, and Client Contract Services tools and templates
• Explain the costing process to people without a financial background
• Understand operational department tasks, roles, and cost drivers within ICON
• Solicit input and review contracts and change orders from relevant operational departments
• Review and challenge supporting information for budget changes to ensure changes are reasonable and justified
• Understand legal language in MSAs, Start-up Agreements, and standalone contracts
• Develop cash-neutral payment schedules as required
• Identify issues requiring Legal, operations, or senior management review
• Liaise with Contract Managers on issues escalated within ICON or to clients
• Provide project and financial analysis to support project-team budget information before client submission
• Update Salesforce with accurate contract and change-order status information
• Develop and maintain client/project files and tracking tools
• Manage and prioritize workload around timelines and client submissions
• Review client/project documents and budgets before final Contract Manager quality-control review
• Build relationships with project teams, sales, proposals, finance, project analysis, clients, service areas, and vendors
• Communicate contract and change-order status clearly with project teams and clients
• Provide information for client negotiations and discussions
• Organize, lead, chair, and manage internal and client-related meetings
• Contribute to process improvement and streamlined processes

Contract Analyst II

• Oversee and manage clinical trial activities according to protocol, regulatory requirements, and industry standards
• Lead clinical trial monitoring tasks requiring technical depth, with a focus on quality and continuous improvement
• Monitor clinical trial sites for adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards
• Conduct site visits to assess site performance, resolve issues, and support successful trial execution
• Collaborate with cross-functional teams to ensure timely and accurate data collection and reporting
• Provide training and guidance to site staff and other CRAs
• Build and maintain relationships with site personnel and stakeholders

• Lead statistical methodologies and contribute to the design and analysis of clinical studies
• Oversee biostatistics workstreams, ensuring deliverables meet quality and timeline expectations
• Design and implement statistical analysis plans for clinical trials, aligned with study objectives and regulatory guidelines
• Oversee statistical analysis of clinical data and provide insights and interpretations for decision-making and reporting
• Collaborate with clinical, regulatory, and data management teams
• Mentor junior statisticians and provide training on statistical methodologies and software applications
• Contribute to regulatory submissions and publications
• Stay updated on industry trends and advancements in statistical methodologies
• Participate in protocol development and provide input on endpoints and statistical considerations

Senior Principal Biostatistician

• Oversee and manage clinical trial activities according to protocol, regulatory requirements, and industry standards
• Lead clinical trial monitoring tasks requiring technical depth, with a focus on quality and continuous improvement
• Monitor clinical trial sites for adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards
• Conduct site visits to assess site performance, resolve issues, and support successful trial execution
• Collaborate with cross-functional teams to ensure timely and accurate data collection and reporting
• Provide training and guidance to site staff and other CRAs
• Build and maintain relationships with site personnel and stakeholders to facilitate smooth trial operations

• Serve as the primary point of contact between investigational sites and the sponsor
• Conduct site selection, initiation, routine monitoring, and close-out visits
• Ensure site compliance with ICH-GCP, SOPs, and regulations
• Maintain documentation in CTMS and eTMF systems
• Support site staff training and maintain compliance records
• Monitor patient safety and ensure timely AE/SAE/PQC reporting
• Support subject recruitment and retention efforts
• Oversee drug accountability and proper storage, return, or destruction
• Resolve data queries and drive timely, high-quality data entry
• Document site progress and escalate risks or issues to the clinical team
• Assist with site budgets and timely site payments
• Collaborate with CTAs, LTMs, CTMs, and other cross-functional partners

Senior Supervising Radiologist

Manager, Clinical Operations

Senior Manager, HR Business Partner

Clinical Trial Associate

Senior Clinical Research Associate

Contract Analyst I

Senior Clinical Trial Manager

Payment Analyst

Research Pharmacist

Contract Analyst II

Senior Clinical Research Associate

Senior Principal Biostatistician

Senior Clinical Research Associate

Clinical Research Associate II